Methylscaper: an R/Shiny app for joint visualization of DNA methylation and nucleosome occupancy in single-molecule and single-cell data

SUMMARY: Differential DNA methylation and chromatin accessibility are associated with disease development, particularly cancer. Methods that allow profiling of these epigenetic mechanisms in the same reaction and at the single-molecule or single-cell level continue to emerge. However, a challenge li...

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Detalles Bibliográficos
Autores principales: Knight, Parker, Gauthier, Marie-Pierre L, Pardo, Carolina E, Darst, Russell P, Kapadia, Kevin, Browder, Hadley, Morton, Eliza, Riva, Alberto, Kladde, Michael P, Bacher, Rhonda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665741/
https://www.ncbi.nlm.nih.gov/pubmed/34125875
http://dx.doi.org/10.1093/bioinformatics/btab438

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