Development of an Innovative Berberine Food-Grade Formulation with an Ameliorated Absorption: In Vitro Evidence Confirmed by Healthy Human Volunteers Pharmacokinetic Study

OBJECTIVE: To evaluate in vitro solubility, bioaccessibility, and cytotoxic profile, together with a pharmacokinetic profile by oral administration to healthy volunteers of a novel food-grade berberine formulation (BBR-PP, i.e., berberine Phytosome®). RESULTS: An in vitro increase of solubility in s...

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Detalles Bibliográficos
Autores principales: Petrangolini, Giovanna, Corti, Fabrizio, Ronchi, Massimo, Arnoldi, Lolita, Allegrini, Pietro, Riva, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665891/
https://www.ncbi.nlm.nih.gov/pubmed/34904017
http://dx.doi.org/10.1155/2021/7563889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665891/
https://www.ncbi.nlm.nih.gov/pubmed/34904017
http://dx.doi.org/10.1155/2021/7563889

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