Nonclinical study and applicability of the absorbed dose conversion method with a single biodistribution measurement for targeted alpha-nuclide therapy

BACKGROUND: We recently reported a new absorbed dose conversion method, RAP (RAtio of Pharmacokinetics), for (211)At-meta-astatobenzylguanidine ((211)At-MABG) using a single biodistribution measurement, the percent injected dose/g. However, there were some mathematical ambiguities in determining the...

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Detalles Bibliográficos
Autores principales: Sakashita, Tetsuya, Matsumoto, Shojiro, Watanabe, Shigeki, Hanaoka, Hirofumi, Ohshima, Yasuhiro, Ikoma, Yoko, Ukon, Naoyuki, Sasaki, Ichiro, Higashi, Tatsuya, Higuchi, Tetsuya, Tsushima, Yoshito, Ishioka, Noriko S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665908/
https://www.ncbi.nlm.nih.gov/pubmed/34897556
http://dx.doi.org/10.1186/s40658-021-00425-z

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