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Design and Production An Effective Bispecific Tandem Chimeric Antigen Receptor on T Cells against CD123 and Folate Receptor ß towards B-Acute Myeloid Leukaemia Blasts

OBJECTIVE: The clinical studies of acute myeloid leukaemia (AML) revealed that antigen escaping variants cause cancer recurrence even after treatment with chimeric antigen receptor (CAR)-T cells that target a single tumour antigen. Due to the heterogeneous expression of antigens on leukaemia blasts,...

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Detalles Bibliográficos
Autores principales:	Ghamari, Ali, Pakzad, Parviz, Majd, Ahmad, Ebrahimi, Marzieh, Hamidieh, Amir Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665988/ https://www.ncbi.nlm.nih.gov/pubmed/34939758 http://dx.doi.org/10.22074/cellj.2021.7314

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