Interferon-γ induces interleukin-6 production by neutrophils via the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway

OBJECTIVE: Interferon-gamma (IFN-γ) is overexpressed in rheumatoid synovium and thought to be involved in the pathogenesis of rheumatoid arthritis (RA). In this study, we examined our hypothesis that IFN-γ activates innate immune cells and upregulates inflammatory cytokines. Peripheral blood neutrop...

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Detalles Bibliográficos
Autores principales: Yoshida, Shuhei, Yamada, Shunya, Yokose, Kohei, Matsumoto, Haruki, Fujita, Yuya, Asano, Tomoyuki, Matsuoka, Naoki, Temmoku, Jumpei, Sato, Shuzo, Yoshiro-Furuya, Makiko, Watanabe, Hiroshi, Migita, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666078/
https://www.ncbi.nlm.nih.gov/pubmed/34895310
http://dx.doi.org/10.1186/s13104-021-05860-w

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