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Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients
OBJECTVE: To assess the impact of glycemic variability on blood pressure in hospitalized patients with cardiac disease. METHODS: In 40 patients with cardiovascular disease, the glucose levels were monitored by flash continuous glucose monitoring (FGM; Free-Style Libre™ or Free-Style Libre Pro; Abbot...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japanese Society of Internal Medicine
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666227/ https://www.ncbi.nlm.nih.gov/pubmed/34092728 http://dx.doi.org/10.2169/internalmedicine.6784-20 |
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author | Shimizu, Tomohiro Uzui, Hiroyasu Sato, Yusuke Miyoshi, Machiko Shiomi, Yuichiro Hasegawa, Kanae Ikeda, Hiroyuki Tama, Naoto Fukuoka, Yoshitomo Morishita, Tetsuji Ishida, Kentaro Miyazaki, Shinsuke Tada, Hiroshi |
author_facet | Shimizu, Tomohiro Uzui, Hiroyasu Sato, Yusuke Miyoshi, Machiko Shiomi, Yuichiro Hasegawa, Kanae Ikeda, Hiroyuki Tama, Naoto Fukuoka, Yoshitomo Morishita, Tetsuji Ishida, Kentaro Miyazaki, Shinsuke Tada, Hiroshi |
author_sort | Shimizu, Tomohiro |
collection | PubMed |
description | OBJECTVE: To assess the impact of glycemic variability on blood pressure in hospitalized patients with cardiac disease. METHODS: In 40 patients with cardiovascular disease, the glucose levels were monitored by flash continuous glucose monitoring (FGM; Free-Style Libre™ or Free-Style Libre Pro; Abbott, Witney, UK) and self-monitoring blood glucose (SMBG) for 14 days. Blood pressure measurements were performed twice daily (morning and evening) at the same time as the glucose level measurement using SMBG. RESULTS: The detection rate of hypoglycemia using the FGM method was significantly higher than that with the 5-point SMBG method (77.5% vs. 5.0%, p<0.001). Changes in the systolic blood pressure from evening to the next morning [morning - evening (ME) difference] were significantly correlated with night glucose variability (r=0.63, P<0.001). A multiple regression analysis showed that night glucose variability using FGM was more closely correlated with the ME difference [r=0.62 (95% confidence interval, 0.019-0.051); p<0.001] than with the age, body mass index, or smoking history. Night glucose variability was also more closely associated with the ME difference in patients with unstable angina pectoris (UAP) than in those with acute myocardial infarction (AMI) or heart failure (HF) (r=0.83, p=0.058). CONCLUSION: Night glucose variability is associated with the ME blood pressure difference, and FGM is more accurate than the 5-point SMBG approach for detecting such variability. |
format | Online Article Text |
id | pubmed-8666227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-86662272021-12-28 Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients Shimizu, Tomohiro Uzui, Hiroyasu Sato, Yusuke Miyoshi, Machiko Shiomi, Yuichiro Hasegawa, Kanae Ikeda, Hiroyuki Tama, Naoto Fukuoka, Yoshitomo Morishita, Tetsuji Ishida, Kentaro Miyazaki, Shinsuke Tada, Hiroshi Intern Med Original Article OBJECTVE: To assess the impact of glycemic variability on blood pressure in hospitalized patients with cardiac disease. METHODS: In 40 patients with cardiovascular disease, the glucose levels were monitored by flash continuous glucose monitoring (FGM; Free-Style Libre™ or Free-Style Libre Pro; Abbott, Witney, UK) and self-monitoring blood glucose (SMBG) for 14 days. Blood pressure measurements were performed twice daily (morning and evening) at the same time as the glucose level measurement using SMBG. RESULTS: The detection rate of hypoglycemia using the FGM method was significantly higher than that with the 5-point SMBG method (77.5% vs. 5.0%, p<0.001). Changes in the systolic blood pressure from evening to the next morning [morning - evening (ME) difference] were significantly correlated with night glucose variability (r=0.63, P<0.001). A multiple regression analysis showed that night glucose variability using FGM was more closely correlated with the ME difference [r=0.62 (95% confidence interval, 0.019-0.051); p<0.001] than with the age, body mass index, or smoking history. Night glucose variability was also more closely associated with the ME difference in patients with unstable angina pectoris (UAP) than in those with acute myocardial infarction (AMI) or heart failure (HF) (r=0.83, p=0.058). CONCLUSION: Night glucose variability is associated with the ME blood pressure difference, and FGM is more accurate than the 5-point SMBG approach for detecting such variability. The Japanese Society of Internal Medicine 2021-06-05 2021-11-15 /pmc/articles/PMC8666227/ /pubmed/34092728 http://dx.doi.org/10.2169/internalmedicine.6784-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Shimizu, Tomohiro Uzui, Hiroyasu Sato, Yusuke Miyoshi, Machiko Shiomi, Yuichiro Hasegawa, Kanae Ikeda, Hiroyuki Tama, Naoto Fukuoka, Yoshitomo Morishita, Tetsuji Ishida, Kentaro Miyazaki, Shinsuke Tada, Hiroshi Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients |
title | Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients |
title_full | Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients |
title_fullStr | Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients |
title_full_unstemmed | Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients |
title_short | Association between Changes in the Systolic Blood Pressure from Evening to the Next Morning and Night Glucose Variability in Heart Disease Patients |
title_sort | association between changes in the systolic blood pressure from evening to the next morning and night glucose variability in heart disease patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666227/ https://www.ncbi.nlm.nih.gov/pubmed/34092728 http://dx.doi.org/10.2169/internalmedicine.6784-20 |
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