Loss of SMARCB1 promotes autophagy and facilitates tumour progression in chordoma by transcriptionally activating ATG5

OBJECTIVES: SWI/SNF‐related matrix‐associated actin‐dependent regulator of chromatin subfamily B member 1 (SMARCB1) loss is associated with a poor prognosis in chordoma, while the mechanism remains largely unclear. Here, we aim to explore the function and regulatory mechanisms of SMARCB1 in chordoma...

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Detalles Bibliográficos
Autores principales: Li, Mingxuan, Shen, Yutao, Xiong, Yujia, Wang, Shuai, Li, Chuzhong, Bai, Jiwei, Zhang, Yazhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666275/
https://www.ncbi.nlm.nih.gov/pubmed/34668612
http://dx.doi.org/10.1111/cpr.13136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666275/
https://www.ncbi.nlm.nih.gov/pubmed/34668612
http://dx.doi.org/10.1111/cpr.13136

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