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Deletion of Nf2 in neural crest‐derived tongue mesenchyme alters tongue shape and size, Hippo signalling and cell proliferation in a region‐ and stage‐specific manner

OBJECTIVES: The mammalian tongue develops from the branchial arches (1–4) and comprises highly organized tissues compartmentalized by mesenchyme/connective tissue that is largely derived from neural crest (NC). This study aimed to understand the roles of tumour suppressor Neurofibromin 2 (Nf2) in NC...

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Detalles Bibliográficos
Autores principales: Ishan, Mohamed, Chen, Guiqian, Yu, Wenxin, Wang, Zhonghou, Giovannini, Marco, Cao, Xinwei, Liu, Hong‐Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666282/
https://www.ncbi.nlm.nih.gov/pubmed/34697858
http://dx.doi.org/10.1111/cpr.13144

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