Cargando…

Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling

OBJECTIVES: Previous reports have proposed the importance of signalling and material exchange between cartilage and subchondral bone. However, the specific experimental evidence is still insufficient to support the effect of this interdependent relationship on mutual cell behaviours. In this study,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yueyi, Zhang, Demao, Guo, Daimo, Li, Jiachi, Xu, Siqun, Wei, Jieya, Xie, Jing, Zhou, Xuedong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666287/ https://www.ncbi.nlm.nih.gov/pubmed/34726809 http://dx.doi.org/10.1111/cpr.13156

Ejemplares similares

Osteoblasts induce glucose-derived ATP perturbations in chondrocytes through noncontact communication: Osteoblasts induce glucose-derived ATP perturbations in chondrocytes
por: Wei, Jieya, et al.
Publicado: (2022)

SDF-1α Promotes Chondrocyte Autophagy through CXCR4/mTOR Signaling Axis
por: Li, Jiazhou, et al.
Publicado: (2023)

FGF19 induces the cell cycle arrest at G2-phase in chondrocytes
por: Chen, Hao, et al.
Publicado: (2023)

Transforming growth factor-β1-induced N-cadherin drives cell–cell communication through connexin43 in osteoblast lineage
por: Yang, Yueyi, et al.
Publicado: (2021)

Microenvironmental stiffness mediates cytoskeleton re-organization in chondrocytes through laminin-FAK mechanotransduction
por: Zhou, Chenchen, et al.
Publicado: (2022)

FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPKα-p38/MAPK pathway
por: Kan, Shiyi, et al.
Publicado: (2023)

Correction: FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPKα-p38/MAPK pathway
por: Kan, Shiyi, et al.
Publicado: (2023)

Runx1 protects against the pathological progression of osteoarthritis
por: Zhou, Chenchen, et al.
Publicado: (2021)

CTGF facilitates cell‐cell communication in chondrocytes via PI3K/Akt signalling pathway
por: Wu, Zuping, et al.
Publicado: (2021)

TGF‐β1 promotes gap junctions formation in chondrocytes via Smad3/Smad4 signalling
por: Wang, Qingxuan, et al.
Publicado: (2018)

Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9
por: Kohn, Anat, et al.
Publicado: (2015)

Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes
por: Xiao, Di, et al.
Publicado: (2019)

The role of mechano growth factor in chondrocytes and cartilage defects: a concise review: Role of mechano growth factor in chondrocytes and cartilage defects
por: Liu, Yi, et al.
Publicado: (2023)

Osteoblast-Chondrocyte Interactions in Osteoarthritis
por: Findlay, David M., et al.
Publicado: (2014)

Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest
por: Shang, Xifu, et al.
Publicado: (2016)

On the evolutionary relationship between chondrocytes and osteoblasts
por: Gómez-Picos, Patsy, et al.
Publicado: (2015)

Cell Death in Chondrocytes, Osteoblasts, and Osteocytes
por: Komori, Toshihisa
Publicado: (2016)

Galectin-3 Inhibits Osteoblast Differentiation through Notch Signaling()()
por: Nakajima, Kosei, et al.
Publicado: (2014)

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts
por: Qin, Xin, et al.
Publicado: (2020)

Chondrocyte‐to‐osteoblast transformation in mandibular fracture repair
por: Wong, Sarah A., et al.
Publicado: (2020)

EFTUD2 gene deficiency disrupts osteoblast maturation and inhibits chondrocyte differentiation via activation of the p53 signaling pathway
por: Wu, Jing, et al.
Publicado: (2019)

MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes
por: Kostopoulou, Fotini, et al.
Publicado: (2015)

Excessive mechanical stretch-mediated osteoblasts promote the catabolism and apoptosis of chondrocytes via the Wnt/β-catenin signaling pathway
por: Song, Cheng-Xian, et al.
Publicado: (2021)

Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation
por: Aghajanian, Patrick, et al.
Publicado: (2017)

Direct Reprogramming of Mouse Subchondral Bone Osteoblasts into Chondrocyte-like Cells
por: Li, Meihan, et al.
Publicado: (2022)

Influence of Cholesterol on the Regulation of Osteoblast Function
por: Akhmetshina, Alena, et al.
Publicado: (2023)

Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes
por: Minguzzi, Manuela, et al.
Publicado: (2021)

Notch Signaling Regulates the Chondrogenic Potential of Both Articular Chondrocytes and Their Progenitors During Expansion
por: Kurenkova, Anastasiia D, et al.
Publicado: (2023)

A novel in vitro assay to study chondrocyte-to-osteoblast transdifferentiation
por: Tschaffon, Miriam E. A., et al.
Publicado: (2021)

Extracellular Vesicles Allow Epigenetic Mechanotransduction between Chondrocytes and Osteoblasts
por: Shang, Xiaobin, et al.
Publicado: (2021)

Effects of Modulation of the Hedgehog and Notch Signaling Pathways on Osteoblast Differentiation Induced by Titanium with Nanotopography
por: Souza, Paola Gomes, et al.
Publicado: (2023)

BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells
por: Cui, Jing, et al.
Publicado: (2018)

Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9
por: Chen, Shan, et al.
Publicado: (2013)

Directing the osteoblastic and chondrocytic differentiations of mesenchymal stem cells: matrix vs. induction media
por: He, Jing, et al.
Publicado: (2017)

Stiffened fibre-like microenvironment based on patterned equidistant micropillars directs chondrocyte hypertrophy
por: Duan, Mengmeng, et al.
Publicado: (2023)

Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling
por: Fujita, Takashi, et al.
Publicado: (2004)

Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells
por: Steppe, Lena, et al.
Publicado: (2022)

Acute Lymphoblastic Leukemia Cells Inhibit the Differentiation of Bone Mesenchymal Stem Cells into Osteoblasts In Vitro by Activating Notch Signaling
por: Yang, Gui-Cun, et al.
Publicado: (2015)

MYL3 protects chondrocytes from senescence by inhibiting clathrin-mediated endocytosis and activating of Notch signaling
por: Cao, He, et al.
Publicado: (2023)

NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts
por: Ye, Ling, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_34gbcr50202o2dt1nuo6kat17e