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COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study

Globally, vaccine hesitancy is a growing public health problem. It is detrimental to the consolidation of immunization program achievements and elimination of vaccine-targeted diseases. The objective of this study was to estimate the prevalence of COVID-19 vaccine hesitancy in China and explore its...

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Autores principales: Wu, Jian, Li, Quanman, Silver Tarimo, Clifford, Wang, Meiyun, Gu, Jianqin, Wei, Wei, Ma, Mingze, Zhao, Lipei, Mu, Zihan, Miao, Yudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666422/
https://www.ncbi.nlm.nih.gov/pubmed/34912346
http://dx.doi.org/10.3389/fimmu.2021.781161
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author Wu, Jian
Li, Quanman
Silver Tarimo, Clifford
Wang, Meiyun
Gu, Jianqin
Wei, Wei
Ma, Mingze
Zhao, Lipei
Mu, Zihan
Miao, Yudong
author_facet Wu, Jian
Li, Quanman
Silver Tarimo, Clifford
Wang, Meiyun
Gu, Jianqin
Wei, Wei
Ma, Mingze
Zhao, Lipei
Mu, Zihan
Miao, Yudong
author_sort Wu, Jian
collection PubMed
description Globally, vaccine hesitancy is a growing public health problem. It is detrimental to the consolidation of immunization program achievements and elimination of vaccine-targeted diseases. The objective of this study was to estimate the prevalence of COVID-19 vaccine hesitancy in China and explore its contributing factors. A national cross-sectional online survey among Chinese adults (≥18 years old) was conducted between August 6, 2021 and August 9 via a market research company. We collected sociodemographic information; lifestyle behavior; quality of life; the knowledge, awareness, and behavior of COVID-19; the knowledge, awareness, and behavior of COVID-19 vaccine; willingness of COVID-19 vaccination; accessibility of COVID-19 vaccination services; skepticism about COVID-19 and COVID-19 vaccine; doctor and vaccine developer scale; and so on. Odds ratios (OR) with 95% confidence intervals (CI) were used to estimate the associations by using logistic regression models. A total of 29,925 residents (48.64% men) were enrolled in our study with mean age of 30.99 years. We found an overall prevalence of COVID-19 vaccine hesitancy at 8.40% (95% CI, 8.09–8.72) in primary vaccination and 8.39% (95% CI, 8.07–8.70) in booster vaccination. In addition, after adjusting for potential confounders, we found that women, higher educational level, married residents, higher score of health condition, never smoked, increased washing hands, increased wearing mask, increased social distance, lower level of vaccine conspiracy beliefs, disease risks outweigh vaccine risk, higher level of convenient vaccination, and higher level of trust in doctor and developer were more willing to vaccinate than all others (all p < 0.05). Age, sex, educational level, marital status, chronic disease condition, smoking, healthy behaviors, the curability of COVID-19, the channel of accessing information of COVID-19 vaccine, endorsement of vaccine conspiracy beliefs, weigh risks of vaccination against risks of the disease, making a positive influence on the health of others around you, and lower trust in healthcare system may affect the variation of willingness to take a COVID-19 vaccine (all p < 0.05). The prevalence of COVID-19 vaccine hesitancy was modest in China, even with the slight resulting cascade of changing vaccination rates between the primary and booster vaccination. Urgent action to address vaccine hesitancy is needed in building trust in medical personnel and vaccine producers, promoting the convenience of vaccination services, and spreading reliable information of COVID-19 vaccination via the Internet and other media.
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spelling pubmed-86664222021-12-14 COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study Wu, Jian Li, Quanman Silver Tarimo, Clifford Wang, Meiyun Gu, Jianqin Wei, Wei Ma, Mingze Zhao, Lipei Mu, Zihan Miao, Yudong Front Immunol Immunology Globally, vaccine hesitancy is a growing public health problem. It is detrimental to the consolidation of immunization program achievements and elimination of vaccine-targeted diseases. The objective of this study was to estimate the prevalence of COVID-19 vaccine hesitancy in China and explore its contributing factors. A national cross-sectional online survey among Chinese adults (≥18 years old) was conducted between August 6, 2021 and August 9 via a market research company. We collected sociodemographic information; lifestyle behavior; quality of life; the knowledge, awareness, and behavior of COVID-19; the knowledge, awareness, and behavior of COVID-19 vaccine; willingness of COVID-19 vaccination; accessibility of COVID-19 vaccination services; skepticism about COVID-19 and COVID-19 vaccine; doctor and vaccine developer scale; and so on. Odds ratios (OR) with 95% confidence intervals (CI) were used to estimate the associations by using logistic regression models. A total of 29,925 residents (48.64% men) were enrolled in our study with mean age of 30.99 years. We found an overall prevalence of COVID-19 vaccine hesitancy at 8.40% (95% CI, 8.09–8.72) in primary vaccination and 8.39% (95% CI, 8.07–8.70) in booster vaccination. In addition, after adjusting for potential confounders, we found that women, higher educational level, married residents, higher score of health condition, never smoked, increased washing hands, increased wearing mask, increased social distance, lower level of vaccine conspiracy beliefs, disease risks outweigh vaccine risk, higher level of convenient vaccination, and higher level of trust in doctor and developer were more willing to vaccinate than all others (all p < 0.05). Age, sex, educational level, marital status, chronic disease condition, smoking, healthy behaviors, the curability of COVID-19, the channel of accessing information of COVID-19 vaccine, endorsement of vaccine conspiracy beliefs, weigh risks of vaccination against risks of the disease, making a positive influence on the health of others around you, and lower trust in healthcare system may affect the variation of willingness to take a COVID-19 vaccine (all p < 0.05). The prevalence of COVID-19 vaccine hesitancy was modest in China, even with the slight resulting cascade of changing vaccination rates between the primary and booster vaccination. Urgent action to address vaccine hesitancy is needed in building trust in medical personnel and vaccine producers, promoting the convenience of vaccination services, and spreading reliable information of COVID-19 vaccination via the Internet and other media. Frontiers Media S.A. 2021-11-29 /pmc/articles/PMC8666422/ /pubmed/34912346 http://dx.doi.org/10.3389/fimmu.2021.781161 Text en Copyright © 2021 Wu, Li, Silver Tarimo, Wang, Gu, Wei, Ma, Zhao, Mu and Miao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Wu, Jian
Li, Quanman
Silver Tarimo, Clifford
Wang, Meiyun
Gu, Jianqin
Wei, Wei
Ma, Mingze
Zhao, Lipei
Mu, Zihan
Miao, Yudong
COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study
title COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study
title_full COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study
title_fullStr COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study
title_full_unstemmed COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study
title_short COVID-19 Vaccine Hesitancy Among Chinese Population: A Large-Scale National Study
title_sort covid-19 vaccine hesitancy among chinese population: a large-scale national study
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666422/
https://www.ncbi.nlm.nih.gov/pubmed/34912346
http://dx.doi.org/10.3389/fimmu.2021.781161
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