MIR337-3p Enhances Mycobacterial Pathogenicity Involving TLR4/MYD88 and STAT3 Signals, Impairing VDR Antimicrobial Response and Fast-Acting Immunity

Active form of vitamin D (VitD) enhances human innate immunity against Mycobacterium tuberculosis (Mtb) infection. Our previous studies showed that MIR337-3p was highly expressed in lymphocytes of tuberculosis (TB) patients. Here, we identified the mechanism of MIR337-3p in the regulation of fast-ac...

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Detalles Bibliográficos
Autores principales: Liang, Shanshan, Huang, Guixian, Wu, Tian, Peng, Ying, Liu, Xi, Ji, Xuejiao, Sha, Wei, Wang, Feifei, Shen, Ling, Shen, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666424/
https://www.ncbi.nlm.nih.gov/pubmed/34912331
http://dx.doi.org/10.3389/fimmu.2021.739219

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