A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis

BACKGROUND: Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis. CASE PRESENTATION: A young woman presented with acute neuropsychiatric symptoms following rec...

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Autores principales: Takata, Junko, Durkin, Simon M., Wong, Solomon, Zandi, Michael S., Swanton, Josephine K., Corrah, Tumena W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666465/
https://www.ncbi.nlm.nih.gov/pubmed/34903200
http://dx.doi.org/10.1186/s12883-021-02517-w
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author Takata, Junko
Durkin, Simon M.
Wong, Solomon
Zandi, Michael S.
Swanton, Josephine K.
Corrah, Tumena W.
author_facet Takata, Junko
Durkin, Simon M.
Wong, Solomon
Zandi, Michael S.
Swanton, Josephine K.
Corrah, Tumena W.
author_sort Takata, Junko
collection PubMed
description BACKGROUND: Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis. CASE PRESENTATION: A young woman presented with acute neuropsychiatric symptoms following recent ChAdOx1 nCoV-19 vaccination. Extensive investigation did not identify alternative causes. CONCLUSIONS: This difficult case is here described, including presentation, investigation, and management. Further study on neuropsychiatric side-effects of COVID-19 vaccination, including investigation as to whether there may be a causal link, is required.
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spelling pubmed-86664652021-12-13 A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis Takata, Junko Durkin, Simon M. Wong, Solomon Zandi, Michael S. Swanton, Josephine K. Corrah, Tumena W. BMC Neurol Case Report BACKGROUND: Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis. CASE PRESENTATION: A young woman presented with acute neuropsychiatric symptoms following recent ChAdOx1 nCoV-19 vaccination. Extensive investigation did not identify alternative causes. CONCLUSIONS: This difficult case is here described, including presentation, investigation, and management. Further study on neuropsychiatric side-effects of COVID-19 vaccination, including investigation as to whether there may be a causal link, is required. BioMed Central 2021-12-13 /pmc/articles/PMC8666465/ /pubmed/34903200 http://dx.doi.org/10.1186/s12883-021-02517-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Takata, Junko
Durkin, Simon M.
Wong, Solomon
Zandi, Michael S.
Swanton, Josephine K.
Corrah, Tumena W.
A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis
title A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis
title_full A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis
title_fullStr A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis
title_full_unstemmed A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis
title_short A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis
title_sort case report of chadox1 ncov-19 vaccine–associated encephalitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666465/
https://www.ncbi.nlm.nih.gov/pubmed/34903200
http://dx.doi.org/10.1186/s12883-021-02517-w
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