Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report

Levothyroxine remains the standard therapy for patients with hypothyroidism worldwide. Levothyroxine allergy is rarely seen and alternative therapies are less efficacious and scarcely available. The use of liothyronine (LT3) monotherapy is less favoured due to its short half-life and unpredictable p...

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Autores principales: Jiang, Chua Yi, Shen, Bay Shing, Yun, Taye Zhi, Singarayar, Carolina, Hui, Foo Siew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the ASEAN Federation of Endocrine Societies 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666481/
https://www.ncbi.nlm.nih.gov/pubmed/34966208
http://dx.doi.org/10.15605/jafes.036.02.10
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author Jiang, Chua Yi
Shen, Bay Shing
Yun, Taye Zhi
Singarayar, Carolina
Hui, Foo Siew
author_facet Jiang, Chua Yi
Shen, Bay Shing
Yun, Taye Zhi
Singarayar, Carolina
Hui, Foo Siew
author_sort Jiang, Chua Yi
collection PubMed
description Levothyroxine remains the standard therapy for patients with hypothyroidism worldwide. Levothyroxine allergy is rarely seen and alternative therapies are less efficacious and scarcely available. The use of liothyronine (LT3) monotherapy is less favoured due to its short half-life and unpredictable pharmacological profile. We report a 59-year-old male with a hypersensitivity reaction to levothyroxine who was successfully desensitized with oral levothyroxine within a day using a 14-step protocol.
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spelling pubmed-86664812021-12-28 Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report Jiang, Chua Yi Shen, Bay Shing Yun, Taye Zhi Singarayar, Carolina Hui, Foo Siew J ASEAN Fed Endocr Soc Case Report Levothyroxine remains the standard therapy for patients with hypothyroidism worldwide. Levothyroxine allergy is rarely seen and alternative therapies are less efficacious and scarcely available. The use of liothyronine (LT3) monotherapy is less favoured due to its short half-life and unpredictable pharmacological profile. We report a 59-year-old male with a hypersensitivity reaction to levothyroxine who was successfully desensitized with oral levothyroxine within a day using a 14-step protocol. Journal of the ASEAN Federation of Endocrine Societies 2021-08-19 2021 /pmc/articles/PMC8666481/ /pubmed/34966208 http://dx.doi.org/10.15605/jafes.036.02.10 Text en © 2021 Journal of the ASEAN Federation of Endocrine Societies https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
spellingShingle Case Report
Jiang, Chua Yi
Shen, Bay Shing
Yun, Taye Zhi
Singarayar, Carolina
Hui, Foo Siew
Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report
title Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report
title_full Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report
title_fullStr Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report
title_full_unstemmed Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report
title_short Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy: A Case Report
title_sort successful oral levothyroxine desensitization in a patient with severe hypothyroidism post radioactive iodine therapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666481/
https://www.ncbi.nlm.nih.gov/pubmed/34966208
http://dx.doi.org/10.15605/jafes.036.02.10
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