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Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma

In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laborato...

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Detalles Bibliográficos
Autores principales: Bao, Daorina, Tan, Ying, Yu, Xiaojuan, Wang, Bingjie, Wang, Hui, Xu, Rong, Zhou, Fude, Zhao, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666564/
https://www.ncbi.nlm.nih.gov/pubmed/34912821
http://dx.doi.org/10.3389/fmed.2021.759279
Descripción
Sumario:In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laboratory criteria, which showed impaired renal function and nephrotic syndrome with predominant hematuria. Renal biopsy showed IV+V lupus nephritis with highly infiltrated lymphoid cells in the kidney. Secondary lupus nephritis was suspected based on the possible pathogenesis of glomerular injury due to mantle cell lymphoma. Low-dose dexamethasone, rituximab, and lenalidomide were immediately started on the patient, and his renal function was improved after the first cycle of chemotherapy.