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METTL1 promotes hepatocarcinogenesis via m(7)G tRNA modification‐dependent translation control

BACKGROUND: N(7)‐methylguanosine (m(7)G) modification is one of the most common transfer RNA (tRNA) modifications in humans. The precise function and molecular mechanism of m(7)G tRNA modification in hepatocellular carcinoma (HCC) remain poorly understood. METHODS: The prognostic value and expressio...

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Detalles Bibliográficos
Autores principales: Chen, Zhihang, Zhu, Wanjie, Zhu, Shenghua, Sun, Kaiyu, Liao, Junbin, Liu, Haining, Dai, Zihao, Han, Hui, Ren, Xuxin, Yang, Qingxia, Zheng, Siyi, Peng, Baogang, Peng, Sui, Kuang, Ming, Lin, Shuibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666584/
https://www.ncbi.nlm.nih.gov/pubmed/34898034
http://dx.doi.org/10.1002/ctm2.661