Cargando…
METTL1 promotes hepatocarcinogenesis via m(7)G tRNA modification‐dependent translation control
BACKGROUND: N(7)‐methylguanosine (m(7)G) modification is one of the most common transfer RNA (tRNA) modifications in humans. The precise function and molecular mechanism of m(7)G tRNA modification in hepatocellular carcinoma (HCC) remain poorly understood. METHODS: The prognostic value and expressio...
Autores principales: | Chen, Zhihang, Zhu, Wanjie, Zhu, Shenghua, Sun, Kaiyu, Liao, Junbin, Liu, Haining, Dai, Zihao, Han, Hui, Ren, Xuxin, Yang, Qingxia, Zheng, Siyi, Peng, Baogang, Peng, Sui, Kuang, Ming, Lin, Shuibin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666584/ https://www.ncbi.nlm.nih.gov/pubmed/34898034 http://dx.doi.org/10.1002/ctm2.661 |
Ejemplares similares
-
METTL1 promotes neuroblastoma development through m(7)G tRNA modification and selective oncogenic gene translation
por: Huang, Ying, et al.
Publicado: (2022) -
Molecular basis for human mitochondrial tRNA m(3)C modification by alternatively spliced METTL8
por: Huang, Meng-Han, et al.
Publicado: (2022) -
METTL3-mediated m(6)A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway
por: Han, Hui, et al.
Publicado: (2021) -
N(7)-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis
por: Han, Hui, et al.
Publicado: (2022) -
METTL3-Mediated m(6)A RNA Modification Regulates Corneal Injury Repair
por: Dai, Yarong, et al.
Publicado: (2021)