A Novel Type of PD-L1 Inhibitor rU1 snRNPA From Human-Derived Protein Scaffolds Library

Three marketed anti-PD-L1 antibodies almost have severe immune-mediated side effects. The therapeutic effects of anti-PD-L1 chemical inhibitors are not satisfied in the clinical trials. Here we constructed human-derived protein scaffolds library and screened scaffolds with a shape complementary to t...

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Detalles Bibliográficos
Autores principales: Ma, Chuang, Qiao, Sennan, Liu, Zhiyi, Shan, Liang, Liang, Chongyang, Fan, Meiling, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666589/
https://www.ncbi.nlm.nih.gov/pubmed/34912719
http://dx.doi.org/10.3389/fonc.2021.781046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666589/
https://www.ncbi.nlm.nih.gov/pubmed/34912719
http://dx.doi.org/10.3389/fonc.2021.781046

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