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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

The adenosine-triphosphate-(ATP)-binding cassette (ABC) transporter ABCA7 is a genetic risk factor for Alzheimer’s disease (AD). Defective ABCA7 promotes AD development and/or progression. Unfortunately, ABCA7 belongs to the group of ‘under-studied’ ABC transporters that cannot be addressed by small...

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Detalles Bibliográficos
Autores principales:	Namasivayam, Vigneshwaran, Stefan, Katja, Pahnke, Jens, Stefan, Sven Marcel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666613/ https://www.ncbi.nlm.nih.gov/pubmed/34976306 http://dx.doi.org/10.1016/j.csbj.2021.11.035

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