Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells

OBJECTIVES: Coeliac disease (CD) is a complex autoimmune disorder that develops in genetically susceptible individuals. Dietary gluten triggers an immune response for which the only available treatment so far is a strict, lifelong gluten free diet. Human leucocyte antigen (HLA) genes and several non...

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Detalles Bibliográficos
Autores principales: Olazagoitia-Garmendia, Ane, Zhang, Linda, Mera, Paula, Godbout, Julie K, Sebastian-DelaCruz, Maialen, Garcia-Santisteban, Iraia, Mendoza, Luis Manuel, Huerta, Alain, Irastorza, Iñaki, Bhagat, Govind, Green, Peter H, Herrero, Laura, Serra, Dolors, Rodriguez, Jose Antonio, Verdu, Elena F, He, Chuan, Bilbao, Jose Ramon, Castellanos-Rubio, Ainara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Coeliac Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666699/
https://www.ncbi.nlm.nih.gov/pubmed/33526437
http://dx.doi.org/10.1136/gutjnl-2020-322566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666699/
https://www.ncbi.nlm.nih.gov/pubmed/33526437
http://dx.doi.org/10.1136/gutjnl-2020-322566

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