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Process control and in silico modeling strategies for enabling high density culture of human pluripotent stem cells in stirred tank bioreactors

The routine therapeutic and industrial applications of human pluripotent stem cells (hPSCs) require their constant mass supply by robust, efficient, and economically viable bioprocesses. Our protocol describes the fully controlled expansion of hPSCs in stirred tank bioreactors (STBRs) enabling cell...

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Detalles Bibliográficos
Autores principales:	Manstein, Felix, Ullmann, Kevin, Triebert, Wiebke, Zweigerdt, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666714/ https://www.ncbi.nlm.nih.gov/pubmed/34917976 http://dx.doi.org/10.1016/j.xpro.2021.100988

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