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The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique
Although the epidemiological studies provide evidence for an increased risk of lung cancer risk associated with residential radon, an issue of radon-thoron discrimination remains to be solved. In this study, an updated evaluation of lung cancer risk among the residents in Gansu, China was performed...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666718/ https://www.ncbi.nlm.nih.gov/pubmed/34912771 http://dx.doi.org/10.3389/fpubh.2021.764201 |
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author | Kudo, Hiromi Yoshinaga, Shinji Li, Xiaoliang Lei, Shujie Zhang, Shouzhi Sun, Quanfu Koriyama, Chihaya Akiba, Suminori Tokonami, Shinji |
author_facet | Kudo, Hiromi Yoshinaga, Shinji Li, Xiaoliang Lei, Shujie Zhang, Shouzhi Sun, Quanfu Koriyama, Chihaya Akiba, Suminori Tokonami, Shinji |
author_sort | Kudo, Hiromi |
collection | PubMed |
description | Although the epidemiological studies provide evidence for an increased risk of lung cancer risk associated with residential radon, an issue of radon-thoron discrimination remains to be solved. In this study, an updated evaluation of lung cancer risk among the residents in Gansu, China was performed where one of the major epidemiological studies on indoor radon demonstrated an increased risk of lung cancer. We analyzed data from a hospital-based case-control study that included 30 lung cancer cases and 39 controls with special attention to internal exposure assessment based on the discriminative measurement technique of radon isotopes. Results from the analyses showed non-significant increased lung cancer risks; odds ratios (ORs) adjusted for age, smoking, and total income were 0.35 (95% CI: 0.07–1.74) and 0.27 (95% CI: 0.04–1.74) for groups living in residences with indoor radon concentrations of 50–100 Bq m(−3) and over 100 Bq m(−3), respectively, compared with those with < 50 Bq m(−3) indoor radon concentrations. Although the small sample size hampers the usefulness of present analyses, our study suggests that reevaluation of lung cancer risk associated with residential radon in the epidemiological studies will be required on the basis of precise exposure assessment. |
format | Online Article Text |
id | pubmed-8666718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86667182021-12-14 The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique Kudo, Hiromi Yoshinaga, Shinji Li, Xiaoliang Lei, Shujie Zhang, Shouzhi Sun, Quanfu Koriyama, Chihaya Akiba, Suminori Tokonami, Shinji Front Public Health Public Health Although the epidemiological studies provide evidence for an increased risk of lung cancer risk associated with residential radon, an issue of radon-thoron discrimination remains to be solved. In this study, an updated evaluation of lung cancer risk among the residents in Gansu, China was performed where one of the major epidemiological studies on indoor radon demonstrated an increased risk of lung cancer. We analyzed data from a hospital-based case-control study that included 30 lung cancer cases and 39 controls with special attention to internal exposure assessment based on the discriminative measurement technique of radon isotopes. Results from the analyses showed non-significant increased lung cancer risks; odds ratios (ORs) adjusted for age, smoking, and total income were 0.35 (95% CI: 0.07–1.74) and 0.27 (95% CI: 0.04–1.74) for groups living in residences with indoor radon concentrations of 50–100 Bq m(−3) and over 100 Bq m(−3), respectively, compared with those with < 50 Bq m(−3) indoor radon concentrations. Although the small sample size hampers the usefulness of present analyses, our study suggests that reevaluation of lung cancer risk associated with residential radon in the epidemiological studies will be required on the basis of precise exposure assessment. Frontiers Media S.A. 2021-11-29 /pmc/articles/PMC8666718/ /pubmed/34912771 http://dx.doi.org/10.3389/fpubh.2021.764201 Text en Copyright © 2021 Kudo, Yoshinaga, Li, Lei, Zhang, Sun, Koriyama, Akiba and Tokonami. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Kudo, Hiromi Yoshinaga, Shinji Li, Xiaoliang Lei, Shujie Zhang, Shouzhi Sun, Quanfu Koriyama, Chihaya Akiba, Suminori Tokonami, Shinji The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
title | The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
title_full | The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
title_fullStr | The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
title_full_unstemmed | The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
title_short | The First Attempt to Reevaluate Radon and Thoron Exposure in Gansu Province Study Using Radon-Thoron Discriminating Measurement Technique |
title_sort | first attempt to reevaluate radon and thoron exposure in gansu province study using radon-thoron discriminating measurement technique |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666718/ https://www.ncbi.nlm.nih.gov/pubmed/34912771 http://dx.doi.org/10.3389/fpubh.2021.764201 |
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