Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma

OBJECTIVE: Intrahepatic cholangiocarcinoma (ICC)—a rare liver malignancy with limited therapeutic options—is characterised by aggressive progression, desmoplasia and vascular abnormalities. The aim of this study was to determine the role of placental growth factor (PlGF) in ICC progression. DESIGN:...

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Detalles Bibliográficos
Autores principales: Aoki, Shuichi, Inoue, Koetsu, Klein, Sebastian, Halvorsen, Stefan, Chen, Jiang, Matsui, Aya, Nikmaneshi, Mohammad R, Kitahara, Shuji, Hato, Tai, Chen, Xianfeng, Kawakubo, Kazumichi, Nia, Hadi T, Chen, Ivy, Schanne, Daniel H, Mamessier, Emilie, Shigeta, Kohei, Kikuchi, Hiroto, Ramjiawan, Rakesh R, Schmidt, Tyge CE, Iwasaki, Masaaki, Yau, Thomas, Hong, Theodore S, Quaas, Alexander, Plum, Patrick S, Dima, Simona, Popescu, Irinel, Bardeesy, Nabeel, Munn, Lance L, Borad, Mitesh J, Sassi, Slim, Jain, Rakesh K., Zhu, Andrew X, Duda, Dan G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666816/
https://www.ncbi.nlm.nih.gov/pubmed/33431577
http://dx.doi.org/10.1136/gutjnl-2020-322493

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