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PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF

OBJECTIVE: Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) pathophysiology remains unclear. This study aims to characterise the molecular basis of HBV-ACLF using transcriptomics. METHODS: Four hundred subjects with HBV-ACLF, acute-on-chronic hepatic dysfunction (ACHD), liver cirr...

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Detalles Bibliográficos
Autores principales: Li, Jiang, Liang, Xi, Jiang, Jing, Yang, Lingling, Xin, Jiaojiao, Shi, Dongyan, Lu, Yingyan, Li, Jun, Ren, Keke, Hassan, Hozeifa Mohamed, Zhang, Jianing, Chen, Pengcheng, Yao, Heng, Li, Jiaqi, Wu, Tianzhou, Jin, Linfeng, Ye, Ping, Li, Tan, Zhang, Huafen, Sun, Suwan, Guo, Beibei, Zhou, Xingping, Cai, Qun, Chen, Jiaxian, Xu, Xiaowei, Huang, Jianrong, Hao, Shaorui, He, Jinqiu, Xin, Shaojie, Wang, Di, Trebicka, Jonel, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666828/
https://www.ncbi.nlm.nih.gov/pubmed/33431576
http://dx.doi.org/10.1136/gutjnl-2020-323395