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Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence

OBJECTIVES: Alterations in the intestinal microbiota are linked with a wide range of autoimmune and inflammatory conditions, including inflammatory bowel diseases (IBD), where pathobionts penetrate the intestinal barrier and promote inflammatory reactions. In patients with IBD, the ability of intest...

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Detalles Bibliográficos
Autores principales:	Spalinger, Marianne Rebecca, Shawki, Ali, Chatterjee, Pritha, Canale, Vinicius, Santos, Alina, Sayoc-Becerra, Anica, Scharl, Michael, Tremblay, Michel L, Borneman, James, McCole, Declan F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Gut Microbiota
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8666829/ https://www.ncbi.nlm.nih.gov/pubmed/33563644 http://dx.doi.org/10.1136/gutjnl-2020-323636

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