Cargando…

Syngeneic bone marrow transplantation in combination with PI3K inhibitor reversed hyperglycemia in later-stage streptozotocin-induced diabetes

BACKGROUND: Type 1 diabetes (T1D) is a multiple factor autoimmune disease characterized by T cell-mediated immune destruction of islet β cells. Autologous hematopoietic stem cell transplantation (AHSCT) has been a novel strategy for patients with new-onset T1D, but not for those with a later diagnos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shiyun, Dai, Qianqian, Zhang, Bin, Liu, Siyang, Wang, Ying, Zhang, Yixue, Chen, Dongyue, Zong, Ningning, Wang, Hongwei, Ding, Jingjing, Gao, Qian, Wen, Yanting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667114/ https://www.ncbi.nlm.nih.gov/pubmed/34988151 http://dx.doi.org/10.21037/atm-21-3329

Ejemplares similares

Inhibition of phosphoinositide‑3 kinases γ/δ ameliorates pulmonary granuloma by rescuing Treg function in a sarcoidosis model
por: Zhang, Xian, et al.
Publicado: (2023)

Insulin-Producing Cells Differentiated from Human Bone Marrow Mesenchymal Stem Cells In Vitro Ameliorate Streptozotocin-Induced Diabetic Hyperglycemia
por: Xin, Ying, et al.
Publicado: (2016)

Hepatic immunophenotyping for streptozotocin-induced hyperglycemia in mice
por: Lee, Young-Sun, et al.
Publicado: (2016)

Deletion of the Men1 Gene Prevents Streptozotocin-Induced Hyperglycemia in Mice
por: Yang, Yuqing, et al.
Publicado: (2010)

Investigation of Intestinal Absorption and Excretion of Paracetamol in Streptozotocin-Induced Hyperglycemia
por: Mészáros, Petra, et al.
Publicado: (2022)

Leptin Therapy Reverses Hyperglycemia in Mice With Streptozotocin-Induced Diabetes, Independent of Hepatic Leptin Signaling
por: Denroche, Heather C., et al.
Publicado: (2011)

Autophagy in Muscle of Glucose-Infusion Hyperglycemia Rats and Streptozotocin-Induced Hyperglycemia Rats via Selective Activation of m-TOR or FoxO3
por: Lv, Pengfei, et al.
Publicado: (2014)

Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model
por: Rytelewski, Mateusz, et al.
Publicado: (2020)

Astaxanthin Protects against Hyperglycemia-Induced Oxidative and Inflammatory Damage to Bone Marrow and to Bone Marrow-Retained Stem Cells and Restores Normal Hematopoiesis in Streptozotocin-Induced Diabetic Mice
por: Bhattarai, Govinda, et al.
Publicado: (2022)

Recombinant betatrophin (Angptl-8/lipasin) ameliorates streptozotocin-induced hyperglycemia and β-cell destruction in neonatal rats
por: Zhang, Di, et al.
Publicado: (2019)

Streptozotocin-induced hyperglycemia alters the cecal metabolome and exacerbates antibiotic-induced dysbiosis
por: Wurster, Jenna I., et al.
Publicado: (2021)

Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes
por: Peng, Shiqin, et al.
Publicado: (2018)

β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia
por: Egerod, Kristoffer L., et al.
Publicado: (2011)

Streptozotocin-Induced Hyperglycemia Is Associated with Unique Microbiome Metabolomic Signatures in Response to Ciprofloxacin Treatment
por: Wurster, Jenna I., et al.
Publicado: (2022)

Hyperglycemia and reduced adiposity of streptozotocin-induced diabetic mice are not alleviated by oral benzylamine supplementation
por: Carpéné, Christian, et al.
Publicado: (2022)

PROLIFERATION OF DONOR MARROW AND THYMUS CELLS IN THE MYELOID AND LYMPHOID ORGANS OF IRRADIATED SYNGENEIC HOST MICE
por: Takada, Akikazu, et al.
Publicado: (1973)

Exosomes from β-cells alleviated hyperglycemia and enhanced angiogenesis in islets of streptozotocin-induced diabetic mice
por: Sun, Yun, et al.
Publicado: (2019)

Intrapancreatic injection of human bone marrow-derived mesenchymal stem/stromal cells alleviates hyperglycemia and modulates the macrophage state in streptozotocin-induced type 1 diabetic mice
por: Murai, Norimitsu, et al.
Publicado: (2017)

Extension of Maximal Lifespan and High Bone Marrow Chimerism After Nonmyeloablative Syngeneic Transplantation of Bone Marrow From Young to Old Mice
por: Kovina, Marina V., et al.
Publicado: (2019)

Osteogenesis of bone marrow mesenchymal stem cell in hyperglycemia
por: Luo, Meng, et al.
Publicado: (2023)

Failure of syngeneic bone marrow cells to protect against MC-induced lymphoma in dba-2 mice.
por: Chen, L., et al.
Publicado: (1968)

Comparison of gamma and x-ray irradiation for myeloablation and establishment of normal and autoimmune syngeneic bone marrow chimeras
por: Wittenborn, Thomas Rea, et al.
Publicado: (2021)

Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia
por: Larsen, Steen, et al.
Publicado: (2015)

Mild hyperglycemia triggered islet function recovery in streptozotocin‐induced insulin‐deficient diabetic rats
por: Cheng, Yu, et al.
Publicado: (2016)

Effects of Talinum triangulare leaf flavonoid extract on streptozotocin‐induced hyperglycemia and associated complications in rats
por: Oluba, Olarewaju M., et al.
Publicado: (2018)

Orthosiphon stamineus as a potential antidiabetic drug in maternal hyperglycemia in streptozotocin-induced diabetic rats
por: Lokman, Ezarul Faradianna, et al.
Publicado: (2019)

Downregulation of Candidate Gene Expression and Neuroprotection by Piperine in Streptozotocin-Induced Hyperglycemia and Memory Impairment in Rats
por: Kumar, Suresh, et al.
Publicado: (2021)

Rosinidin Flavonoid Ameliorates Hyperglycemia, Lipid Pathways and Proinflammatory Cytokines in Streptozotocin-Induced Diabetic Rats
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Averrhoa bilimbi fruits attenuate hyperglycemia-mediated oxidative stress in streptozotocin-induced diabetic rats
por: Kurup, Surya B., et al.
Publicado: (2016)

Honey proteins regulate oxidative stress, inflammation and ameliorates hyperglycemia in streptozotocin induced diabetic rats
por: Naqvi, Farwa, et al.
Publicado: (2023)

Streptozotocin-Induced Hyperglycemia Affects the Pharmacokinetics of Koumine and its Anti-Allodynic Action in a Rat Model of Diabetic Neuropathic Pain
por: Ye, Li-Xiang, et al.
Publicado: (2021)

Retraction: Autophagy in Muscle of Glucose-Infusion Hyperglycemia Rats and Streptozotocin-Induced Hyperglycemia Rats via Selective Activation of m-TOR or FoxO3
Publicado: (2019)

Systemic Delivery of mLIGHT-Armed Myxoma Virus Is Therapeutic for Later-Stage Syngeneic Murine Lung Metastatic Osteosarcoma
por: Christie, John D., et al.
Publicado: (2022)

MHC-Linked Syngeneic Developmental Preference in Thymic Lobes Colonized with Bone Marrow Cells: A Mathematical model
por: Mehr, Ramit, et al.
Publicado: (1998)

BONE MARROW AS SOURCE OF CELLS IN REACTIONS OF CELLULAR HYPERSENSITIVITY : I. PASSIVE TRANSFER OF TUBERCULIN SENSITIVITY IN SYNGENEIC SYSTEMS
por: Lubaroff, David M., et al.
Publicado: (1968)

Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution
Publicado: (1983)

MSCs Become Collagen-Type I Producing Cells with Different Phenotype in Allogeneic and Syngeneic Bone Marrow Transplantation
por: Rusch, Robert Maximilian, et al.
Publicado: (2021)

Persistent correction of hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice by a non-conventional radical scavenger
por: Novelli, M., et al.
Publicado: (2010)

Extract of Sesbania grandiflora Ameliorates Hyperglycemia in High Fat Diet-Streptozotocin Induced Experimental Diabetes Mellitus
por: Panigrahi, Ghanshyam, et al.
Publicado: (2016)

Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys
por: Chen, Chung-Ming, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0flodeger5m161e6gtj4aq447d