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A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells
BACKGROUND: Mosaic loss of Y chromosome (LOY) is the most common somatic change that occurs in circulating white blood cells of older men. LOY in leukocytes is associated with increased risk for all-cause mortality and a range of common disease such as hematological and non-hematological cancer, Alz...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667399/ https://www.ncbi.nlm.nih.gov/pubmed/34895331 http://dx.doi.org/10.1186/s13578-021-00716-z |