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A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells

BACKGROUND: Mosaic loss of Y chromosome (LOY) is the most common somatic change that occurs in circulating white blood cells of older men. LOY in leukocytes is associated with increased risk for all-cause mortality and a range of common disease such as hematological and non-hematological cancer, Alz...

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Detalles Bibliográficos
Autores principales:	Riaz, Moeen, Mattisson, Jonas, Polekhina, Galina, Bakshi, Andrew, Halvardson, Jonatan, Danielsson, Marcus, Ameur, Adam, McNeil, John, Forsberg, Lars A., Lacaze, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667399/ https://www.ncbi.nlm.nih.gov/pubmed/34895331 http://dx.doi.org/10.1186/s13578-021-00716-z

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