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Mortality by opioid poisoning in children and teenagers and opioid prescriptions
BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid presc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667418/ https://www.ncbi.nlm.nih.gov/pubmed/34903210 http://dx.doi.org/10.1186/s12887-021-03061-9 |
Sumario: | BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England. METHODS: A retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning. RESULTS: The number of opioid prescriptions decreased over the study period (− 2.4%, p < 0.001). Most deaths due to opioid poisoning in children and teenagers were seen in those under one year old and those aged between 15 and 19 years old (Kruskal-Wallis: p = 0.12; Dunn’s test: p = 0.01). Deaths in all age ranges did not change significantly (Poisson Regression Analysis: p > 0.05). CONCLUSION: Despite the reduction in community opioid prescriptions, there was no decrease in the number of deaths in children and teenagers due to opioid poisoning. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-03061-9. |
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