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Mortality by opioid poisoning in children and teenagers and opioid prescriptions
BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid presc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667418/ https://www.ncbi.nlm.nih.gov/pubmed/34903210 http://dx.doi.org/10.1186/s12887-021-03061-9 |
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author | Cranfield, Elise Ashcroft, Elizabeth Forget, Patrice |
author_facet | Cranfield, Elise Ashcroft, Elizabeth Forget, Patrice |
author_sort | Cranfield, Elise |
collection | PubMed |
description | BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England. METHODS: A retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning. RESULTS: The number of opioid prescriptions decreased over the study period (− 2.4%, p < 0.001). Most deaths due to opioid poisoning in children and teenagers were seen in those under one year old and those aged between 15 and 19 years old (Kruskal-Wallis: p = 0.12; Dunn’s test: p = 0.01). Deaths in all age ranges did not change significantly (Poisson Regression Analysis: p > 0.05). CONCLUSION: Despite the reduction in community opioid prescriptions, there was no decrease in the number of deaths in children and teenagers due to opioid poisoning. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-03061-9. |
format | Online Article Text |
id | pubmed-8667418 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-86674182021-12-13 Mortality by opioid poisoning in children and teenagers and opioid prescriptions Cranfield, Elise Ashcroft, Elizabeth Forget, Patrice BMC Pediatr Research BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England. METHODS: A retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning. RESULTS: The number of opioid prescriptions decreased over the study period (− 2.4%, p < 0.001). Most deaths due to opioid poisoning in children and teenagers were seen in those under one year old and those aged between 15 and 19 years old (Kruskal-Wallis: p = 0.12; Dunn’s test: p = 0.01). Deaths in all age ranges did not change significantly (Poisson Regression Analysis: p > 0.05). CONCLUSION: Despite the reduction in community opioid prescriptions, there was no decrease in the number of deaths in children and teenagers due to opioid poisoning. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-03061-9. BioMed Central 2021-12-13 /pmc/articles/PMC8667418/ /pubmed/34903210 http://dx.doi.org/10.1186/s12887-021-03061-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Cranfield, Elise Ashcroft, Elizabeth Forget, Patrice Mortality by opioid poisoning in children and teenagers and opioid prescriptions |
title | Mortality by opioid poisoning in children and teenagers and opioid prescriptions |
title_full | Mortality by opioid poisoning in children and teenagers and opioid prescriptions |
title_fullStr | Mortality by opioid poisoning in children and teenagers and opioid prescriptions |
title_full_unstemmed | Mortality by opioid poisoning in children and teenagers and opioid prescriptions |
title_short | Mortality by opioid poisoning in children and teenagers and opioid prescriptions |
title_sort | mortality by opioid poisoning in children and teenagers and opioid prescriptions |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667418/ https://www.ncbi.nlm.nih.gov/pubmed/34903210 http://dx.doi.org/10.1186/s12887-021-03061-9 |
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