Cargando…

Mortality by opioid poisoning in children and teenagers and opioid prescriptions

BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid presc...

Descripción completa

Detalles Bibliográficos
Autores principales: Cranfield, Elise, Ashcroft, Elizabeth, Forget, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667418/
https://www.ncbi.nlm.nih.gov/pubmed/34903210
http://dx.doi.org/10.1186/s12887-021-03061-9
_version_ 1784614383613116416
author Cranfield, Elise
Ashcroft, Elizabeth
Forget, Patrice
author_facet Cranfield, Elise
Ashcroft, Elizabeth
Forget, Patrice
author_sort Cranfield, Elise
collection PubMed
description BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England. METHODS: A retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning. RESULTS: The number of opioid prescriptions decreased over the study period (− 2.4%, p < 0.001). Most deaths due to opioid poisoning in children and teenagers were seen in those under one year old and those aged between 15 and 19 years old (Kruskal-Wallis: p = 0.12; Dunn’s test: p = 0.01). Deaths in all age ranges did not change significantly (Poisson Regression Analysis: p > 0.05). CONCLUSION: Despite the reduction in community opioid prescriptions, there was no decrease in the number of deaths in children and teenagers due to opioid poisoning. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-03061-9.
format Online
Article
Text
id pubmed-8667418
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-86674182021-12-13 Mortality by opioid poisoning in children and teenagers and opioid prescriptions Cranfield, Elise Ashcroft, Elizabeth Forget, Patrice BMC Pediatr Research BACKGROUND: No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England. AIM: To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England. METHODS: A retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning. RESULTS: The number of opioid prescriptions decreased over the study period (− 2.4%, p < 0.001). Most deaths due to opioid poisoning in children and teenagers were seen in those under one year old and those aged between 15 and 19 years old (Kruskal-Wallis: p = 0.12; Dunn’s test: p = 0.01). Deaths in all age ranges did not change significantly (Poisson Regression Analysis: p > 0.05). CONCLUSION: Despite the reduction in community opioid prescriptions, there was no decrease in the number of deaths in children and teenagers due to opioid poisoning. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-03061-9. BioMed Central 2021-12-13 /pmc/articles/PMC8667418/ /pubmed/34903210 http://dx.doi.org/10.1186/s12887-021-03061-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Cranfield, Elise
Ashcroft, Elizabeth
Forget, Patrice
Mortality by opioid poisoning in children and teenagers and opioid prescriptions
title Mortality by opioid poisoning in children and teenagers and opioid prescriptions
title_full Mortality by opioid poisoning in children and teenagers and opioid prescriptions
title_fullStr Mortality by opioid poisoning in children and teenagers and opioid prescriptions
title_full_unstemmed Mortality by opioid poisoning in children and teenagers and opioid prescriptions
title_short Mortality by opioid poisoning in children and teenagers and opioid prescriptions
title_sort mortality by opioid poisoning in children and teenagers and opioid prescriptions
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667418/
https://www.ncbi.nlm.nih.gov/pubmed/34903210
http://dx.doi.org/10.1186/s12887-021-03061-9
work_keys_str_mv AT cranfieldelise mortalitybyopioidpoisoninginchildrenandteenagersandopioidprescriptions
AT ashcroftelizabeth mortalitybyopioidpoisoninginchildrenandteenagersandopioidprescriptions
AT forgetpatrice mortalitybyopioidpoisoninginchildrenandteenagersandopioidprescriptions