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Mitochondrial Targeting and pH-Responsive Nanogels for Co-Delivery of Lonidamine and Paclitaxel to Conquer Drug Resistance

Multidrug resistance (MDR) is one of the leading causes of the failure of cancer chemotherapy and mainly attributed to the overexpression of drug efflux transporters in cancer cells, which is dependent on adenosine triphosphate (ATP). To overcome this phenomenon, herein, a mitochondrial-directed pH-...

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Detalles Bibliográficos
Autores principales:	Chen, Enping, Wang, Ting, Zhang, Junmei, Zhou, Xiang, Niu, Yafan, Liu, Fu, Zhong, Yinan, Huang, Dechun, Chen, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667579/ https://www.ncbi.nlm.nih.gov/pubmed/34912792 http://dx.doi.org/10.3389/fbioe.2021.787320

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