m(6)A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity

N(6)-methyladenosine (m(6)A) RNA modification is a fundamental determinant of mRNA metabolism, but its role in innate immunity-driven non-alcoholic fatty liver disease (NAFLD) and obesity is not known. Here, we show that myeloid lineage-restricted deletion of the m(6)A “writer” protein Methyltransfe...

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Detalles Bibliográficos
Autores principales: Qin, Yanqin, Li, Binghua, Arumugam, Suyavaran, Lu, Qiuxia, Mankash, Salah M., Li, Junzi, Sun, Beicheng, Li, Jiansheng, Flavell, Richard A., Li, Hua-Bing, Ouyang, Xinshou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667589/
https://www.ncbi.nlm.nih.gov/pubmed/34758326
http://dx.doi.org/10.1016/j.celrep.2021.109968

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