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Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae

Neisseria gonorrhoeae is a high-priority pathogen of concern due to the growing prevalence of resistance development against approved antibiotics. Herein, we report the anti-gonococcal activity of ethoxzolamide, the FDA-approved human carbonic anhydrase inhibitor. Ethoxzolamide displayed an MIC(50,)...

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Detalles Bibliográficos
Autores principales:	Abutaleb, Nader S., Elhassanny, Ahmed E. M., Nocentini, Alessio, Hewitt, Chad S., Elkashif, Ahmed, Cooper, Bruce R., Supuran, Claudiu T., Seleem, Mohamed N., Flaherty, Daniel P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667909/ https://www.ncbi.nlm.nih.gov/pubmed/34894972 http://dx.doi.org/10.1080/14756366.2021.1991336

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