Kounis Syndrome: Dexketoprofen-Associated ST-Elevation Myocardial Infarction

Allergic angina and allergic myocardial infarction are common diseases associated with acute coronary syndromes and encompass a wide spectrum of mast cell activation disorders termed “Kounis Syndrome”. We present here a patient with Kounis syndrome presenting with sudden cardiac arrest after intravenous infusion of dexketoprofen in the emergency room. LEARNING POINTS: There are 3 types of Kounis syndrome, of which Type I, allergic coronary vasospasm, is the most common. The most common presentation of Kounis syndrome is ST-elevation myocardial infarction. Although not all cases of Kounis syndrome are reported, they are common in clinical practice and many more causal factors are predicted to play a role in the future.