Cargando…
Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review
Use of a tirofiban bridge is an alternative to simply withdrawing dual antiplatelet therapy prior to operating on patients at high risk of stent thrombosis and bleeding. We aimed to evaluate the efficacy and safety of this protocol in patients undergoing surgery within 12 months of a percutaneous co...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668084/ https://www.ncbi.nlm.nih.gov/pubmed/34925474 http://dx.doi.org/10.1590/1677-5449.210113 |
_version_ | 1784614495331549184 |
---|---|
author | Riscado, Lorrane Vieira Siqueira de Pinho, João Henrique Sendrete Lobato, Armando de Carvalho |
author_facet | Riscado, Lorrane Vieira Siqueira de Pinho, João Henrique Sendrete Lobato, Armando de Carvalho |
author_sort | Riscado, Lorrane Vieira Siqueira |
collection | PubMed |
description | Use of a tirofiban bridge is an alternative to simply withdrawing dual antiplatelet therapy prior to operating on patients at high risk of stent thrombosis and bleeding. We aimed to evaluate the efficacy and safety of this protocol in patients undergoing surgery within 12 months of a percutaneous coronary intervention involving stenting. We performed a systematic review based on searches of the PubMed, Web of Science, Cochrane, Embase, Lilacs, and Scielo databases and of the references of relevant articles on the topic. Five of the 107 studies identified were included after application of eligibility criteria and analysis of methodological quality, totaling 422 patients, 227 in control groups. Notwithstanding the limitations reported, four of the five studies included indicate that the tirofiban bridge technique is effective for reducing adverse cardiac events and is safe in terms of not interfering with the risk of hemorrhagic events or bleeding. However, randomized clinical trials are needed to provide robust evidence. |
format | Online Article Text |
id | pubmed-8668084 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) |
record_format | MEDLINE/PubMed |
spelling | pubmed-86680842021-12-16 Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review Riscado, Lorrane Vieira Siqueira de Pinho, João Henrique Sendrete Lobato, Armando de Carvalho J Vasc Bras Review Article Use of a tirofiban bridge is an alternative to simply withdrawing dual antiplatelet therapy prior to operating on patients at high risk of stent thrombosis and bleeding. We aimed to evaluate the efficacy and safety of this protocol in patients undergoing surgery within 12 months of a percutaneous coronary intervention involving stenting. We performed a systematic review based on searches of the PubMed, Web of Science, Cochrane, Embase, Lilacs, and Scielo databases and of the references of relevant articles on the topic. Five of the 107 studies identified were included after application of eligibility criteria and analysis of methodological quality, totaling 422 patients, 227 in control groups. Notwithstanding the limitations reported, four of the five studies included indicate that the tirofiban bridge technique is effective for reducing adverse cardiac events and is safe in terms of not interfering with the risk of hemorrhagic events or bleeding. However, randomized clinical trials are needed to provide robust evidence. Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2021-12-01 /pmc/articles/PMC8668084/ /pubmed/34925474 http://dx.doi.org/10.1590/1677-5449.210113 Text en Copyright© 2021. The authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Riscado, Lorrane Vieira Siqueira de Pinho, João Henrique Sendrete Lobato, Armando de Carvalho Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review |
title | Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review |
title_full | Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review |
title_fullStr | Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review |
title_full_unstemmed | Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review |
title_short | Efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review |
title_sort | efficacy and safety of tirofiban bridge as an alternative to suspension of dual antiplatelet therapy in patients undergoing surgery: a systematic review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668084/ https://www.ncbi.nlm.nih.gov/pubmed/34925474 http://dx.doi.org/10.1590/1677-5449.210113 |
work_keys_str_mv | AT riscadolorranevieirasiqueira efficacyandsafetyoftirofibanbridgeasanalternativetosuspensionofdualantiplatelettherapyinpatientsundergoingsurgeryasystematicreview AT depinhojoaohenriquesendrete efficacyandsafetyoftirofibanbridgeasanalternativetosuspensionofdualantiplatelettherapyinpatientsundergoingsurgeryasystematicreview AT lobatoarmandodecarvalho efficacyandsafetyoftirofibanbridgeasanalternativetosuspensionofdualantiplatelettherapyinpatientsundergoingsurgeryasystematicreview |