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Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi
INTRODUCTION: Hypertension is a major threat to public health globally. Especially in sub-Saharan African countries, this coexists with high burden of other infectious diseases, creating a complex public health situation which is difficult to address. Tackling this will require targeted public healt...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668094/ https://www.ncbi.nlm.nih.gov/pubmed/34898616 http://dx.doi.org/10.1371/journal.pone.0260225 |
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author | Iradukunda, Arnaud Odjidja, Emmanuel Nene Ndayishima, Stephane Karl Ngendakumana, Egide Ndayishimiye, Gabin Pacifique Sinarinzi, Darlene Izere, Cheilla Ntakaburimvo, Nestor Akimana, Arlene |
author_facet | Iradukunda, Arnaud Odjidja, Emmanuel Nene Ndayishima, Stephane Karl Ngendakumana, Egide Ndayishimiye, Gabin Pacifique Sinarinzi, Darlene Izere, Cheilla Ntakaburimvo, Nestor Akimana, Arlene |
author_sort | Iradukunda, Arnaud |
collection | PubMed |
description | INTRODUCTION: Hypertension is a major threat to public health globally. Especially in sub-Saharan African countries, this coexists with high burden of other infectious diseases, creating a complex public health situation which is difficult to address. Tackling this will require targeted public health intervention based on evidence that well defines the at risk population. In this study, using retrospective data from two referral hospitals in Burundi, we model the risk factors of hypertension in Burundi. MATERIALS AND METHODS: Retrospective data of a sample of 353 randomly selected from a population of 4,380 patients admitted in 2019 in two referral hospitals in Burundi: Military and University teaching hospital of Kamenge. The predictive risk factors were carried out by fixed effect logistic regression. Model performance was assessed with Area under Curve (AUC) method. Model was internally validated using bootstrapping method with 2000 replications. Both data processing and data analysis were done using R software. RESULTS: Overall, 16.7% of the patients were found to be hypertensive. This study didn’t showed any significant difference of hypertension’s prevalences among women (16%) and men (17.7%). After adjustment of the model for cofounding covariates, associated risk factors found were advanced age (40–59 years) and above 60 years, high education level, chronic kidney failure, high body mass index, familial history of hypertension. In absence of these highlighted risk factors, the risk of hypertension occurrence was about 2 per 1000 persons. This probability is more than 90% in patients with more than three risk factors. CONCLUSION: The relatively high prevalence and associated risk factors of hypertension in Burundi raises a call for concern especially in this context where there exist an equally high burden of infectious diseases, other chronic diseases including chronic malnutrition. Targeting interventions based on these identified risk factors will allow judicious channel of resources and effective public health planning. |
format | Online Article Text |
id | pubmed-8668094 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-86680942021-12-14 Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi Iradukunda, Arnaud Odjidja, Emmanuel Nene Ndayishima, Stephane Karl Ngendakumana, Egide Ndayishimiye, Gabin Pacifique Sinarinzi, Darlene Izere, Cheilla Ntakaburimvo, Nestor Akimana, Arlene PLoS One Research Article INTRODUCTION: Hypertension is a major threat to public health globally. Especially in sub-Saharan African countries, this coexists with high burden of other infectious diseases, creating a complex public health situation which is difficult to address. Tackling this will require targeted public health intervention based on evidence that well defines the at risk population. In this study, using retrospective data from two referral hospitals in Burundi, we model the risk factors of hypertension in Burundi. MATERIALS AND METHODS: Retrospective data of a sample of 353 randomly selected from a population of 4,380 patients admitted in 2019 in two referral hospitals in Burundi: Military and University teaching hospital of Kamenge. The predictive risk factors were carried out by fixed effect logistic regression. Model performance was assessed with Area under Curve (AUC) method. Model was internally validated using bootstrapping method with 2000 replications. Both data processing and data analysis were done using R software. RESULTS: Overall, 16.7% of the patients were found to be hypertensive. This study didn’t showed any significant difference of hypertension’s prevalences among women (16%) and men (17.7%). After adjustment of the model for cofounding covariates, associated risk factors found were advanced age (40–59 years) and above 60 years, high education level, chronic kidney failure, high body mass index, familial history of hypertension. In absence of these highlighted risk factors, the risk of hypertension occurrence was about 2 per 1000 persons. This probability is more than 90% in patients with more than three risk factors. CONCLUSION: The relatively high prevalence and associated risk factors of hypertension in Burundi raises a call for concern especially in this context where there exist an equally high burden of infectious diseases, other chronic diseases including chronic malnutrition. Targeting interventions based on these identified risk factors will allow judicious channel of resources and effective public health planning. Public Library of Science 2021-12-13 /pmc/articles/PMC8668094/ /pubmed/34898616 http://dx.doi.org/10.1371/journal.pone.0260225 Text en © 2021 Iradukunda et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Iradukunda, Arnaud Odjidja, Emmanuel Nene Ndayishima, Stephane Karl Ngendakumana, Egide Ndayishimiye, Gabin Pacifique Sinarinzi, Darlene Izere, Cheilla Ntakaburimvo, Nestor Akimana, Arlene Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi |
title | Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi |
title_full | Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi |
title_fullStr | Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi |
title_full_unstemmed | Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi |
title_short | Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi |
title_sort | prevalence and predictive risk factors of hypertension in patients hospitalized in kamenge military hospital and kamenge university teaching hospital in 2019: a fixed effect modelling study in burundi |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668094/ https://www.ncbi.nlm.nih.gov/pubmed/34898616 http://dx.doi.org/10.1371/journal.pone.0260225 |
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