Cargando…

Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi

INTRODUCTION: Hypertension is a major threat to public health globally. Especially in sub-Saharan African countries, this coexists with high burden of other infectious diseases, creating a complex public health situation which is difficult to address. Tackling this will require targeted public healt...

Descripción completa

Detalles Bibliográficos
Autores principales: Iradukunda, Arnaud, Odjidja, Emmanuel Nene, Ndayishima, Stephane Karl, Ngendakumana, Egide, Ndayishimiye, Gabin Pacifique, Sinarinzi, Darlene, Izere, Cheilla, Ntakaburimvo, Nestor, Akimana, Arlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668094/
https://www.ncbi.nlm.nih.gov/pubmed/34898616
http://dx.doi.org/10.1371/journal.pone.0260225
_version_ 1784614497430798336
author Iradukunda, Arnaud
Odjidja, Emmanuel Nene
Ndayishima, Stephane Karl
Ngendakumana, Egide
Ndayishimiye, Gabin Pacifique
Sinarinzi, Darlene
Izere, Cheilla
Ntakaburimvo, Nestor
Akimana, Arlene
author_facet Iradukunda, Arnaud
Odjidja, Emmanuel Nene
Ndayishima, Stephane Karl
Ngendakumana, Egide
Ndayishimiye, Gabin Pacifique
Sinarinzi, Darlene
Izere, Cheilla
Ntakaburimvo, Nestor
Akimana, Arlene
author_sort Iradukunda, Arnaud
collection PubMed
description INTRODUCTION: Hypertension is a major threat to public health globally. Especially in sub-Saharan African countries, this coexists with high burden of other infectious diseases, creating a complex public health situation which is difficult to address. Tackling this will require targeted public health intervention based on evidence that well defines the at risk population. In this study, using retrospective data from two referral hospitals in Burundi, we model the risk factors of hypertension in Burundi. MATERIALS AND METHODS: Retrospective data of a sample of 353 randomly selected from a population of 4,380 patients admitted in 2019 in two referral hospitals in Burundi: Military and University teaching hospital of Kamenge. The predictive risk factors were carried out by fixed effect logistic regression. Model performance was assessed with Area under Curve (AUC) method. Model was internally validated using bootstrapping method with 2000 replications. Both data processing and data analysis were done using R software. RESULTS: Overall, 16.7% of the patients were found to be hypertensive. This study didn’t showed any significant difference of hypertension’s prevalences among women (16%) and men (17.7%). After adjustment of the model for cofounding covariates, associated risk factors found were advanced age (40–59 years) and above 60 years, high education level, chronic kidney failure, high body mass index, familial history of hypertension. In absence of these highlighted risk factors, the risk of hypertension occurrence was about 2 per 1000 persons. This probability is more than 90% in patients with more than three risk factors. CONCLUSION: The relatively high prevalence and associated risk factors of hypertension in Burundi raises a call for concern especially in this context where there exist an equally high burden of infectious diseases, other chronic diseases including chronic malnutrition. Targeting interventions based on these identified risk factors will allow judicious channel of resources and effective public health planning.
format Online
Article
Text
id pubmed-8668094
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-86680942021-12-14 Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi Iradukunda, Arnaud Odjidja, Emmanuel Nene Ndayishima, Stephane Karl Ngendakumana, Egide Ndayishimiye, Gabin Pacifique Sinarinzi, Darlene Izere, Cheilla Ntakaburimvo, Nestor Akimana, Arlene PLoS One Research Article INTRODUCTION: Hypertension is a major threat to public health globally. Especially in sub-Saharan African countries, this coexists with high burden of other infectious diseases, creating a complex public health situation which is difficult to address. Tackling this will require targeted public health intervention based on evidence that well defines the at risk population. In this study, using retrospective data from two referral hospitals in Burundi, we model the risk factors of hypertension in Burundi. MATERIALS AND METHODS: Retrospective data of a sample of 353 randomly selected from a population of 4,380 patients admitted in 2019 in two referral hospitals in Burundi: Military and University teaching hospital of Kamenge. The predictive risk factors were carried out by fixed effect logistic regression. Model performance was assessed with Area under Curve (AUC) method. Model was internally validated using bootstrapping method with 2000 replications. Both data processing and data analysis were done using R software. RESULTS: Overall, 16.7% of the patients were found to be hypertensive. This study didn’t showed any significant difference of hypertension’s prevalences among women (16%) and men (17.7%). After adjustment of the model for cofounding covariates, associated risk factors found were advanced age (40–59 years) and above 60 years, high education level, chronic kidney failure, high body mass index, familial history of hypertension. In absence of these highlighted risk factors, the risk of hypertension occurrence was about 2 per 1000 persons. This probability is more than 90% in patients with more than three risk factors. CONCLUSION: The relatively high prevalence and associated risk factors of hypertension in Burundi raises a call for concern especially in this context where there exist an equally high burden of infectious diseases, other chronic diseases including chronic malnutrition. Targeting interventions based on these identified risk factors will allow judicious channel of resources and effective public health planning. Public Library of Science 2021-12-13 /pmc/articles/PMC8668094/ /pubmed/34898616 http://dx.doi.org/10.1371/journal.pone.0260225 Text en © 2021 Iradukunda et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Iradukunda, Arnaud
Odjidja, Emmanuel Nene
Ndayishima, Stephane Karl
Ngendakumana, Egide
Ndayishimiye, Gabin Pacifique
Sinarinzi, Darlene
Izere, Cheilla
Ntakaburimvo, Nestor
Akimana, Arlene
Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi
title Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi
title_full Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi
title_fullStr Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi
title_full_unstemmed Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi
title_short Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi
title_sort prevalence and predictive risk factors of hypertension in patients hospitalized in kamenge military hospital and kamenge university teaching hospital in 2019: a fixed effect modelling study in burundi
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668094/
https://www.ncbi.nlm.nih.gov/pubmed/34898616
http://dx.doi.org/10.1371/journal.pone.0260225
work_keys_str_mv AT iradukundaarnaud prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT odjidjaemmanuelnene prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT ndayishimastephanekarl prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT ngendakumanaegide prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT ndayishimiyegabinpacifique prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT sinarinzidarlene prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT izerecheilla prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT ntakaburimvonestor prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi
AT akimanaarlene prevalenceandpredictiveriskfactorsofhypertensioninpatientshospitalizedinkamengemilitaryhospitalandkamengeuniversityteachinghospitalin2019afixedeffectmodellingstudyinburundi