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Molecular architecture of the human tRNA ligase complex

RtcB enzymes are RNA ligases that play essential roles in tRNA splicing, unfolded protein response, and RNA repair. In metazoa, RtcB functions as part of a five-subunit tRNA ligase complex (tRNA-LC) along with Ddx1, Cgi-99, Fam98B, and Ashwin. The human tRNA-LC or its individual subunits have been i...

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Detalles Bibliográficos
Autores principales:	Kroupova, Alena, Ackle, Fabian, Asanović, Igor, Weitzer, Stefan, Boneberg, Franziska M, Faini, Marco, Leitner, Alexander, Chui, Alessia, Aebersold, Ruedi, Martinez, Javier, Jinek, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668186/ https://www.ncbi.nlm.nih.gov/pubmed/34854379 http://dx.doi.org/10.7554/eLife.71656

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