Cargando…

ARHGAP11A Promotes the Malignant Progression of Gastric Cancer by Regulating the Stability of Actin Filaments through TPM1

The mechanism underlying the poor prognosis of gastric cancer, including its high degree of malignancy, invasion, and metastasis, is extremely complicated. Rho GTPases are involved in the occurrence and development of a variety of malignant tumors. ARHGAP11A, in the Rho GTPase activating protein fam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guan, Xiaoying, Guan, Xiaoli, Qin, Junjie, Qin, Long, Shi, Wengui, Jiao, Zuoyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668285/ https://www.ncbi.nlm.nih.gov/pubmed/34912455 http://dx.doi.org/10.1155/2021/4146910

Ejemplares similares

Thin filament dysfunctions caused by mutations in tropomyosin Tpm3.12 and Tpm1.1
por: Moraczewska, Joanna
Publicado: (2019)

Recruitment Kinetics of Tropomyosin Tpm3.1 to Actin Filament Bundles in the Cytoskeleton Is Independent of Actin Filament Kinetics
por: Appaduray, Mark A., et al.
Publicado: (2016)

Dynamics of Tpm1.8 domains on actin filaments with single-molecule resolution
por: Bareja, Ilina, et al.
Publicado: (2020)

An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake
por: Kee, Anthony J., et al.
Publicado: (2015)

Interactions of tropomyosin Tpm1.1 on a single actin filament: A method for extraction and processing of high resolution TIRF microscopy data
por: Janco, Miro, et al.
Publicado: (2018)

Mutations Q93H and E97K in TPM2 Disrupt Ca-Dependent Regulation of Actin Filaments
por: Śliwinska, Małgorzata, et al.
Publicado: (2021)

Therapeutic strategies targeting uPAR potentiate anti–PD-1 efficacy in diffuse-type gastric cancer
por: Qin, Long, et al.
Publicado: (2022)

ARHGAP22 Localizes at Endosomes and Regulates Actin Cytoskeleton
por: Mori, Mamiko, et al.
Publicado: (2014)

Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers
por: Naeimzadeh, Y., et al.
Publicado: (2023)

ARHGAP11A Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric Cancer
por: Fan, Biao, et al.
Publicado: (2021)

Implementing TPM
por: Ginder, Andrew, et al.
Publicado: (2020)

TPM4 promotes cell migration by modulating F-actin formation in lung cancer
por: Zhao, Xiaoting, et al.
Publicado: (2019)

MicroRNA-30c-2-3p represses malignant progression of gastric adenocarcinoma cells via targeting ARHGAP11A
por: Zheng, Liang, et al.
Publicado: (2022)

Deletion of the Actin-Associated Tropomyosin Tpm3 Leads to Reduced Cell Complexity in Cultured Hippocampal Neurons—New Insights into the Role of the C-Terminal Region of Tpm3.1
por: Tomanić, Tamara, et al.
Publicado: (2021)

Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer
por: Shi, Wengui, et al.
Publicado: (2021)

Piperazine Derivative Stabilizes Actin Filaments in Primary Fibroblasts and Binds G-Actin In Silico
por: Zernov, Nikita, et al.
Publicado: (2022)

EPLIN regulates actin dynamics by cross-linking and stabilizing filaments
por: Maul, Raymond S., et al.
Publicado: (2003)

Nebulin regulates actin filament lengths by a stabilization mechanism
por: Pappas, Christopher T., et al.
Publicado: (2010)

Myosin and Tropomyosin Stabilize the Conformation of Formin-nucleated Actin Filaments
por: Ujfalusi, Zoltán, et al.
Publicado: (2012)

Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma
por: Dai, Bin, et al.
Publicado: (2018)

ARHGAP15 promotes metastatic colonization in gastric cancer by suppressing RAC1-ROS pathway
por: Zhang, Fei-fei, et al.
Publicado: (2023)

Troponin and a Myopathy-Linked Mutation in TPM3 Inhibit Cofilin-2-Induced Thin Filament Depolymerization
por: Robaszkiewicz, Katarzyna, et al.
Publicado: (2023)

Ticket Processing Management (TPM)
por: Mario David
Publicado: (2006)

Nuclear actin filaments
por: Wells, William A.
Publicado: (2006)

Tropomyosin is essential in yeast, yet the TPM1 and TPM2 products perform distinct functions
Publicado: (1995)

Structural and Functional Peculiarities of Cytoplasmic Tropomyosin Isoforms, the Products of TPM1 and TPM4 Genes
por: Marchenko, Marina, et al.
Publicado: (2021)

Effects of actin filament cross-linking and filament length on actin- myosin interaction
Publicado: (1985)

EhCoactosin Stabilizes Actin Filaments in the Protist Parasite Entamoeba histolytica
por: Kumar, Nitesh, et al.
Publicado: (2014)

TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses
por: Guven, Kim, et al.
Publicado: (2011)

eTPM: A Trusted Cloud Platform Enclave TPM Scheme Based on Intel SGX Technology
por: Sun, Haonan, et al.
Publicado: (2018)

ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility
por: Pham, Alexa K., et al.
Publicado: (2021)

Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex
por: Kalebic, Nereo, et al.
Publicado: (2018)

The Significance of the CLDN18-ARHGAP Fusion Gene in Gastric Cancer: A Systematic Review and Meta-Analysis
por: Zhang, Wei-Han, et al.
Publicado: (2020)

Interaction of actin filaments with microtubules
por: Pollard, T. D., et al.
Publicado: (1984)

Twist response of actin filaments
por: Bibeau, Jeffrey P., et al.
Publicado: (2023)

Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene
por: Luo, Yushuang, et al.
Publicado: (2021)

Yeast actin patches are networks of branched actin filaments
por: Young, Michael E., et al.
Publicado: (2004)

Evidence that calcium may control neurite outgrowth by regulating the stability of actin filaments
Publicado: (1989)

Actin filaments disruption and stabilization affect measles virus maturation by different mechanisms
por: Dietzel, Erik, et al.
Publicado: (2013)

Nonlinear Microscale Mechanics of Actin Networks Governed by Coupling of Filament Crosslinking and Stabilization
por: Dwyer, Mike E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_agckng8b3e2clqndl8i44opd1f