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Thermal Stability Kinetics and Shelf Life Estimation of the Redox-Active Therapeutic and Mimic of Superoxide Dismutase Enzyme, Mn(III) meso-Tetrakis(N-ethylpyridinium-2-yl)porphyrin Chloride (MnTE-2-PyPCl(5), BMX-010)
Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride (MnTE-2-PyPCl(5), BMX-010, and AEOL10113) is among the most studied superoxide dismutase (SOD) mimics and redox-active therapeutics, being currently tested as a drug candidate in a phase II clinical trial on atopic dermatitis and itch....
Autores principales: | Maia, Clarissa G. C., de Araujo, Bárbara C. R., de Freitas-Marques, Maria B., da Costa, Israel F., Yoshida, Maria Irene, da Nova Mussel, Wagner, Sebastião, Rita de Cássia O., Rebouças, Júlio S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668311/ https://www.ncbi.nlm.nih.gov/pubmed/34912497 http://dx.doi.org/10.1155/2021/7003861 |
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