Neuronal activation modulates enhancer activity of genes for excitatory synaptogenesis through de novo DNA methylation

Post-mitotic neurons do exhibit DNA methylation changes, contrary to the longstanding belief that the epigenetic pattern in terminally differentiated cells is essentially unchanged. While the mechanism and physiological significance of DNA demethylation in neurons have been extensively elucidated, t...

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Detalles Bibliográficos
Autores principales: KAMEDA, Tomonori, NAKASHIMA, Hideyuki, TAKIZAWA, Takumi, MIURA, Fumihito, ITO, Takashi, NAKASHIMA, Kinichi, IMAMURA, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668374/
https://www.ncbi.nlm.nih.gov/pubmed/34615840
http://dx.doi.org/10.1262/jrd.2021-106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668374/
https://www.ncbi.nlm.nih.gov/pubmed/34615840
http://dx.doi.org/10.1262/jrd.2021-106

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