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Neuronal activation modulates enhancer activity of genes for excitatory synaptogenesis through de novo DNA methylation
Post-mitotic neurons do exhibit DNA methylation changes, contrary to the longstanding belief that the epigenetic pattern in terminally differentiated cells is essentially unchanged. While the mechanism and physiological significance of DNA demethylation in neurons have been extensively elucidated, t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Society for Reproduction and Development
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668374/ https://www.ncbi.nlm.nih.gov/pubmed/34615840 http://dx.doi.org/10.1262/jrd.2021-106 |