Cargando…

Inflammation and JNK's Role in Niacin-GPR109A Diminished Flushed Effect in Microglial and Neuronal Cells With Relevance to Schizophrenia

Schizophrenia is a neuropsychiatric illness with no single definitive aetiology, making its treatment difficult. Antipsychotics are not fully effective because they treat psychosis rather than the cognitive or negative symptoms. Antipsychotics fail to alleviate symptoms when patients enter the chron...

Descripción completa

Detalles Bibliográficos
Autor principal:	Ansarey, Sabrina H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668869/ https://www.ncbi.nlm.nih.gov/pubmed/34916973 http://dx.doi.org/10.3389/fpsyt.2021.771144

Ejemplares similares

Niacin Ameliorates Neuro-Inflammation in Parkinson’s Disease via GPR109A
por: Giri, Banabihari, et al.
Publicado: (2019)

Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor
por: Adepu, Kiran Kumar, et al.
Publicado: (2021)

The mechanism and mitigation of niacin-induced flushing
por: Kamanna, V S, et al.
Publicado: (2009)

Low-dose niacin supplementation modulates GPR109A, niacin index and ameliorates Parkinson’s disease symptoms without side effects
por: Wakade, Chandramohan, et al.
Publicado: (2015)

The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism
por: Geisler, Caroline E., et al.
Publicado: (2021)

Microglial Phagocytosis of Neurons: Diminishing Neuronal Loss in Traumatic, Infectious, Inflammatory, and Autoimmune CNS Disorders
por: Yanuck, Samuel F.
Publicado: (2019)

Niacin Improves Intestinal Health through Up-Regulation of AQPs Expression Induced by GPR109A
por: Liu, Shilong, et al.
Publicado: (2022)

GPR109A and Vascular Inflammation
por: Chai, Joshua T., et al.
Publicado: (2013)

SKINREMS—A New Method for Assessment of the Niacin Skin Flush Test Response in Schizophrenia
por: Karakula-Juchnowicz, Hanna, et al.
Publicado: (2020)

Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway
por: Guo, Wenjin, et al.
Publicado: (2020)

Involvement of the Niacin Receptor GPR109a in the Local Control of Glucose Uptake in Small Intestine of Type 2 Diabetic Mice
por: Wong, Tung Po, et al.
Publicado: (2015)

Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD(+)/nicotinamide
por: Horimatsu, Tetsuo, et al.
Publicado: (2019)

Impaired Flush Response to Niacin Skin Patch Among Schizophrenia Patients and Their Nonpsychotic Relatives: The Effect of Genetic Loading
por: Chang, Shu-Sen, et al.
Publicado: (2009)

Niacin Skin Flush Backs—From the Roots of the Test to Nowadays Hope
por: Sitarz, Ryszard, et al.
Publicado: (2023)

Niacin skin flush and membrane polyunsaturated fatty acids in schizophrenia from the acute state to partial remission: a dynamic relationship
por: Yu, Ya-Hui, et al.
Publicado: (2022)

Artificial intelligence-assisted niacin skin flush screening in early psychosis identification and prediction
por: Chen, Tao, et al.
Publicado: (2022)

Attenuated niacin-induced skin flush response in individuals with clinical high risk for psychosis
por: Gan, Ranpiao, et al.
Publicado: (2022)

Niacin exacerbates β cell lipotoxicity in diet-induced obesity mice through upregulation of GPR109A and PPARγ2: Inhibition by incretin drugs
por: Zhang, Xiaojing, et al.
Publicado: (2022)

Measuring flushing symptoms with extended-release niacin using the flushing symptom questionnaire©: results from a randomised placebo-controlled clinical trial
por: Paolini, J F, et al.
Publicado: (2008)

Upregulation of GPR109A in Parkinson’s Disease
por: Wakade, Chandramohan, et al.
Publicado: (2014)

GPR109A activation and aging liver
por: Jadeja, Ravirajsinh N., et al.
Publicado: (2019)

Interleukin-6 in Schizophrenia—Is There a Therapeutic Relevance?
por: Borovcanin, Milica Milovan, et al.
Publicado: (2017)

The Role of Inflammation in the Treatment of Schizophrenia
por: Fond, Guillaume, et al.
Publicado: (2020)

GPR17 mediates ischemia-like neuronal injury via microglial activation
por: Zhao, Bing, et al.
Publicado: (2018)

The Basal Forebrain Cholinergic Nuclei and Their Relevance to Schizophrenia and Other Psychotic Disorders
por: Eickhoff, Sofia, et al.
Publicado: (2022)

Complex Gastrointestinal and Endocrine Sources of Inflammation in Schizophrenia
por: Severance, Emily G., et al.
Publicado: (2020)

Editorial: The Role of Inflammation in the Etiology and Treatment of Schizophrenia
por: Köhler-Forsberg, Ole, et al.
Publicado: (2020)

Inflammation and viral infection as disease modifiers in schizophrenia
por: Klein, Hans C., et al.
Publicado: (2023)

Emerging roles of GPR109A in regulation of neuroinflammation in neurological diseases and pain
por: Taing, Kyle, et al.
Publicado: (2022)

Maternal Immune Activation and the Development of Dopaminergic Neurotransmission of the Offspring: Relevance for Schizophrenia and Other Psychoses
por: Aguilar-Valles, Argel, et al.
Publicado: (2020)

BDNF and Schizophrenia: From Neurodevelopment to Neuronal Plasticity, Learning, and Memory
por: Nieto, R., et al.
Publicado: (2013)

Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis
por: Jadeja, Ravirajsinh N., et al.
Publicado: (2019)

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
por: Sun, Yonggan, et al.
Publicado: (2023)

Niacin in Maize
por: Burkholder, Paul R., et al.
Publicado: (1944)

Inflammation and Negative Symptoms of Schizophrenia: Implications for Reward Processing and Motivational Deficits
por: Goldsmith, David R., et al.
Publicado: (2020)

Peripheral inflammation levels associated with degree of advanced brain aging in schizophrenia
por: Klaus, Federica, et al.
Publicado: (2022)

Altered Expression of Glucocorticoid Receptor and Neuron-Specific Enolase mRNA in Peripheral Blood in First-Episode Schizophrenia and Chronic Schizophrenia
por: Liu, Yong, et al.
Publicado: (2020)

Diminishing returns as a function of disturbance
por: Sorjonen, Kimmo, et al.
Publicado: (2020)

M109. WEIGHT GAIN AND THE PATHOPHYSIOLOGY OF SCHIZOPHRENIA
Publicado: (2020)

Diminished Health Returns of Educational Attainment Among Immigrant Adults in the United States
por: Assari, Shervin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5c2pjo8bidb81ss8eotd0qudn1