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Olfactory function testing before and after anesthesia
This study aimed to determine whether anesthesia would affect olfactory function. Patients who were admitted for surgical intervention that did not include the nasal cavity and paranasal sinuses were included in this prospective cohort study. Structured medical history was taken from the patients, i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668874/ https://www.ncbi.nlm.nih.gov/pubmed/34903794 http://dx.doi.org/10.1038/s41598-021-03400-x |
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author | Hernandez, Anna Kristina Fuchss, Patrick Haehner, Antje Hummel, Thomas |
author_facet | Hernandez, Anna Kristina Fuchss, Patrick Haehner, Antje Hummel, Thomas |
author_sort | Hernandez, Anna Kristina |
collection | PubMed |
description | This study aimed to determine whether anesthesia would affect olfactory function. Patients who were admitted for surgical intervention that did not include the nasal cavity and paranasal sinuses were included in this prospective cohort study. Structured medical history was taken from the patients, including the following: age, sex, smoking history, alcohol intake, current medications, and sleep deficits prior to surgery. Before surgery, patients were asked for a self-rating of their olfactory function. Olfactory function was also measured using Sniffin’ Sticks comprising measures of odor threshold, discrimination, and identification. The mean interval between olfactory tests was 6 days (range 3–12 days). Seventy-three patients were included in the study, 34 men and 39 women. Olfactory scores were consistent before and after surgery as indicated by correlative analyses (p < 0.05). Odor thresholds, discrimination, identification, and composite TDI scores did not change significantly, whereas odor identification scores increased (p = 0.011) after surgery. In conclusion, post-operative olfactory scores remained stable. However, identification scores exhibited a slight increase which can be attributed to a retest effect. Overall, the present results indicate that surgery outside of the nasal and paranasal sinus region performed in general anesthesia has no major effect on the sense of smell. |
format | Online Article Text |
id | pubmed-8668874 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-86688742021-12-15 Olfactory function testing before and after anesthesia Hernandez, Anna Kristina Fuchss, Patrick Haehner, Antje Hummel, Thomas Sci Rep Article This study aimed to determine whether anesthesia would affect olfactory function. Patients who were admitted for surgical intervention that did not include the nasal cavity and paranasal sinuses were included in this prospective cohort study. Structured medical history was taken from the patients, including the following: age, sex, smoking history, alcohol intake, current medications, and sleep deficits prior to surgery. Before surgery, patients were asked for a self-rating of their olfactory function. Olfactory function was also measured using Sniffin’ Sticks comprising measures of odor threshold, discrimination, and identification. The mean interval between olfactory tests was 6 days (range 3–12 days). Seventy-three patients were included in the study, 34 men and 39 women. Olfactory scores were consistent before and after surgery as indicated by correlative analyses (p < 0.05). Odor thresholds, discrimination, identification, and composite TDI scores did not change significantly, whereas odor identification scores increased (p = 0.011) after surgery. In conclusion, post-operative olfactory scores remained stable. However, identification scores exhibited a slight increase which can be attributed to a retest effect. Overall, the present results indicate that surgery outside of the nasal and paranasal sinus region performed in general anesthesia has no major effect on the sense of smell. Nature Publishing Group UK 2021-12-13 /pmc/articles/PMC8668874/ /pubmed/34903794 http://dx.doi.org/10.1038/s41598-021-03400-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Hernandez, Anna Kristina Fuchss, Patrick Haehner, Antje Hummel, Thomas Olfactory function testing before and after anesthesia |
title | Olfactory function testing before and after anesthesia |
title_full | Olfactory function testing before and after anesthesia |
title_fullStr | Olfactory function testing before and after anesthesia |
title_full_unstemmed | Olfactory function testing before and after anesthesia |
title_short | Olfactory function testing before and after anesthesia |
title_sort | olfactory function testing before and after anesthesia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668874/ https://www.ncbi.nlm.nih.gov/pubmed/34903794 http://dx.doi.org/10.1038/s41598-021-03400-x |
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