Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP

During translation, a conserved GTPase elongation factor—EF-G in bacteria or eEF2 in eukaryotes—translocates tRNA and mRNA through the ribosome. EF-G has been proposed to act as a flexible motor that propels tRNA and mRNA movement, as a rigid pawl that biases unidirectional translocation resulting f...

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Detalles Bibliográficos
Autores principales: Carbone, Christine E., Loveland, Anna B., Gamper, Howard B., Hou, Ya-Ming, Demo, Gabriel, Korostelev, Andrei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668904/
https://www.ncbi.nlm.nih.gov/pubmed/34903725
http://dx.doi.org/10.1038/s41467-021-27415-0

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