Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice

Early-life exposure to environmental toxins like tobacco can permanently re-program body structure and function. Here, we investigated the long-term effects on mouse adult sleep phenotype exerted by early-life exposure to nicotine or to its principal metabolite, cotinine. Moreover, we investigated w...

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Detalles Bibliográficos
Autores principales: Bastianini, Stefano, Lo Martire, Viviana, Alvente, Sara, Berteotti, Chiara, Matteoli, Gabriele, Rullo, Laura, Stamatakos, Serena, Silvani, Alessandro, Candeletti, Sanzio, Romualdi, Patrizia, Cohen, Gary, Zoccoli, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668915/
https://www.ncbi.nlm.nih.gov/pubmed/34903845
http://dx.doi.org/10.1038/s41598-021-03468-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668915/
https://www.ncbi.nlm.nih.gov/pubmed/34903845
http://dx.doi.org/10.1038/s41598-021-03468-5

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