LncTRPM2-AS inhibits TRIM21-mediated TRPM2 ubiquitination and prevents autophagy-induced apoptosis of macrophages in asthma

Long non-coding RNAs (lncRNAs) play a crucial role in macrophage development but little is known about their role in asthma. Here, we investigated the role of lncRNA lncTRPM2-AS in asthma and found that lncTRPM2-AS participates in the promotion of macrophage inflammation. Downregulation of lncTRPM2-...

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Detalles Bibliográficos
Autores principales: Li, Xiaoping, Wang, Wenwen, Shao, Yu, Zhou, Ji, Huang, Jiaqi, Xu, Fei, Gao, Xiu, Wu, Mengyun, Dong, Yongli, Wu, Wenyan, Cai, Jiamin, Wang, Junyao, Ye, Yunfei, Chen, Zhengrong, Hao, Chuangli, Yang, Yi, Zhang, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668916/
https://www.ncbi.nlm.nih.gov/pubmed/34903714
http://dx.doi.org/10.1038/s41419-021-04437-6

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