α-Synuclein aggregation in the olfactory bulb induces olfactory deficits by perturbing granule cells and granular–mitral synaptic transmission

Olfactory dysfunction is an early pre-motor symptom of Parkinson’s disease (PD) but the neural mechanisms underlying this dysfunction remain largely unknown. Aggregation of α-synuclein is observed in the olfactory bulb (OB) during the early stages of PD, indicating a relationship between α-synuclein...

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Detalles Bibliográficos
Autores principales: Chen, Fengjiao, Liu, Wei, Liu, Penglai, Wang, Zhen, Zhou, You, Liu, Xingyu, Li, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668919/
https://www.ncbi.nlm.nih.gov/pubmed/34903719
http://dx.doi.org/10.1038/s41531-021-00259-7

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