Oh lazy sister, where art thou?

Mitotic divisions achieve equal re-partition of chromosomes into daughter cells. In their recent work in Developmental Cell, Sen, Harrison et al. propose that the risk of mis-segregation in human mitotic cells is higher than previously thought and identify the existence of an early-anaphase correcti...

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Detalles Bibliográficos
Autor principal: Breuer, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668953/
https://www.ncbi.nlm.nih.gov/pubmed/34903809
http://dx.doi.org/10.1038/s42003-021-02933-1
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author Breuer, Manuel
author_facet Breuer, Manuel
author_sort Breuer, Manuel
collection PubMed
description Mitotic divisions achieve equal re-partition of chromosomes into daughter cells. In their recent work in Developmental Cell, Sen, Harrison et al. propose that the risk of mis-segregation in human mitotic cells is higher than previously thought and identify the existence of an early-anaphase correction mechanism. The study documents kinetochore dynamics in unprecedented detail, providing a detailed look at the events preceding loss of correct chromosomal numericity and genomic stability.
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spelling pubmed-86689532022-01-04 Oh lazy sister, where art thou? Breuer, Manuel Commun Biol Research Highlight Mitotic divisions achieve equal re-partition of chromosomes into daughter cells. In their recent work in Developmental Cell, Sen, Harrison et al. propose that the risk of mis-segregation in human mitotic cells is higher than previously thought and identify the existence of an early-anaphase correction mechanism. The study documents kinetochore dynamics in unprecedented detail, providing a detailed look at the events preceding loss of correct chromosomal numericity and genomic stability. Nature Publishing Group UK 2021-12-13 /pmc/articles/PMC8668953/ /pubmed/34903809 http://dx.doi.org/10.1038/s42003-021-02933-1 Text en © Springer Nature Limited 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Highlight
Breuer, Manuel
Oh lazy sister, where art thou?
title Oh lazy sister, where art thou?
title_full Oh lazy sister, where art thou?
title_fullStr Oh lazy sister, where art thou?
title_full_unstemmed Oh lazy sister, where art thou?
title_short Oh lazy sister, where art thou?
title_sort oh lazy sister, where art thou?
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668953/
https://www.ncbi.nlm.nih.gov/pubmed/34903809
http://dx.doi.org/10.1038/s42003-021-02933-1
work_keys_str_mv AT breuermanuel ohlazysisterwhereartthou

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