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A small-molecule compound D6 overcomes EGFR-T790M-mediated resistance in non-small cell lung cancer

Non-small cell lung cancer (NSCLC) is a deadly and highly prevalent malignancy. Targeting activated-EGFR mutations in NSCLC via EGFR tyrosine kinase inhibitor (EGFR-TKI) initially achieves a profound therapeutic response, but resistance frequently evolves, reducing treatment options. Here, we presen...

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Detalles Bibliográficos
Autores principales:	Tang, Xiaolong, Cheng, Lizhi, Li, Guo, Yan, Yong-Ming, Su, Fengting, Huang, Dan-Ling, Zhang, Shuping, Liu, Zuojun, Qian, Minxian, Li, Ji, Cheng, Yong-Xian, Liu, Baohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668973/ https://www.ncbi.nlm.nih.gov/pubmed/34903832 http://dx.doi.org/10.1038/s42003-021-02906-4

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