Therapeutic interfering particles exploiting viral replication and assembly mechanisms show promising performance: a modelling study

Defective interfering particles arise spontaneously during a viral infection as mutants lacking essential parts of the viral genome. Their ability to replicate in the presence of the wild-type (WT) virus (at the expense of viable viral particles) is mimicked and exploited by therapeutic interfering...

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Detalles Bibliográficos
Autores principales: Fatehi, Farzad, Bingham, Richard J., Dechant, Pierre-Philippe, Stockley, Peter G., Twarock, Reidun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668974/
https://www.ncbi.nlm.nih.gov/pubmed/34903795
http://dx.doi.org/10.1038/s41598-021-03168-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668974/
https://www.ncbi.nlm.nih.gov/pubmed/34903795
http://dx.doi.org/10.1038/s41598-021-03168-0

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