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Therapeutic interfering particles exploiting viral replication and assembly mechanisms show promising performance: a modelling study
Defective interfering particles arise spontaneously during a viral infection as mutants lacking essential parts of the viral genome. Their ability to replicate in the presence of the wild-type (WT) virus (at the expense of viable viral particles) is mimicked and exploited by therapeutic interfering...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668974/ https://www.ncbi.nlm.nih.gov/pubmed/34903795 http://dx.doi.org/10.1038/s41598-021-03168-0 |